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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NINL All Species: 8.48
Human Site: S274 Identified Species: 16.97
UniProt: Q9Y2I6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2I6 NP_079452.3 1382 156344 S274 P A L L L E S S T R V K P S K
Chimpanzee Pan troglodytes XP_001150168 1409 159133 S292 P A L L L E S S T R V K P G K
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 A438 G K S L T P S A S T P Y R Q L
Dog Lupus familis XP_534204 1476 166548 S324 P T S L P G S S T L S K P S M
Cat Felis silvestris
Mouse Mus musculus Q6ZQ12 1394 157820 A273 H E P P S L P A S S S L I K P
Rat Rattus norvegicus XP_230778 1394 157847 A273 H E P P S L P A S S S L I K P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 A257 G K S L T P S A S T P Y R Q L
Chicken Gallus gallus XP_426482 2171 248500 A347 A K P L T P S A S T P Y R Q L
Frog Xenopus laevis NP_001086424 1836 213151 S274 S H A P V P I S S T P L K N R
Zebra Danio Brachydanio rerio XP_700610 1713 199360 T252 I N H S K P P T P S A S T P Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P11929 741 84355
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 A328 S L L S S Q I A K R R M Q G M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 24.6 59.3 N.A. 58.3 59.4 N.A. 28.3 26.4 36.9 26.2 N.A. 21.3 N.A. N.A. 27.6
Protein Similarity: 100 95.8 38.7 70.1 N.A. 72.1 72.4 N.A. 42.7 41.1 51.7 45 N.A. 36.1 N.A. N.A. 49.2
P-Site Identity: 100 93.3 13.3 53.3 N.A. 0 0 N.A. 13.3 13.3 6.6 0 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 93.3 26.6 53.3 N.A. 13.3 13.3 N.A. 26.6 26.6 33.3 6.6 N.A. 0 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 17 9 0 0 0 0 50 0 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 17 0 0 0 17 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 0 9 0 0 0 0 0 0 0 17 0 % G
% His: 17 9 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 17 0 0 0 0 0 17 0 0 % I
% Lys: 0 25 0 0 9 0 0 0 9 0 0 25 9 17 17 % K
% Leu: 0 9 25 50 17 17 0 0 0 9 0 25 0 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 17 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 25 0 25 25 9 42 25 0 9 0 34 0 25 9 17 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 0 0 9 25 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 25 9 0 25 0 9 % R
% Ser: 17 0 25 17 25 0 50 34 50 25 25 9 0 17 0 % S
% Thr: 0 9 0 0 25 0 0 9 25 34 0 0 9 0 0 % T
% Val: 0 0 0 0 9 0 0 0 0 0 17 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _