KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMOTL2
All Species:
16.67
Human Site:
S754
Identified Species:
40.74
UniProt:
Q9Y2J4
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2J4
NP_057285.3
779
85750
S754
S
L
L
G
C
S
S
S
Q
R
A
A
S
L
D
Chimpanzee
Pan troglodytes
XP_001143629
985
109690
D909
K
D
S
S
T
Q
T
D
K
S
A
E
L
F
W
Rhesus Macaque
Macaca mulatta
XP_001112164
1057
115216
S1032
S
L
L
G
C
S
S
S
Q
R
A
A
S
L
D
Dog
Lupus familis
XP_542789
913
100134
G888
S
L
L
G
Y
S
G
G
Q
R
T
A
S
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K371
772
85259
S747
G
L
L
G
C
N
S
S
Q
R
T
P
S
L
D
Rat
Rattus norvegicus
NP_113905
773
85569
S748
S
L
L
G
C
N
G
S
Q
R
T
T
S
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513571
1057
116510
T978
T
G
S
R
D
S
S
T
Q
T
D
K
S
S
E
Chicken
Gallus gallus
XP_422675
654
72634
A630
A
Q
G
R
G
E
G
A
E
C
P
A
S
S
P
Frog
Xenopus laevis
NP_001121339
862
97042
S782
K
T
G
S
K
D
N
S
T
Q
T
D
K
N
P
Zebra Danio
Brachydanio rerio
NP_001073646
721
81701
S697
P
E
P
S
T
A
S
S
S
E
S
T
S
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
36.2
72.7
78.6
N.A.
88.9
89.2
N.A.
35.3
58.7
42.6
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
49.6
72.9
79.4
N.A.
90.6
91.1
N.A.
47.5
67.7
58.2
65
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
73.3
N.A.
73.3
73.3
N.A.
26.6
13.3
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
73.3
N.A.
80
80
N.A.
46.6
33.3
20
40
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
10
0
0
30
40
0
0
0
% A
% Cys:
0
0
0
0
40
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
10
0
10
0
0
10
10
0
0
50
% D
% Glu:
0
10
0
0
0
10
0
0
10
10
0
10
0
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
10
20
50
10
0
30
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
20
0
0
0
10
0
0
0
10
0
0
10
10
0
10
% K
% Leu:
0
50
50
0
0
0
0
0
0
0
0
0
10
60
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
20
10
0
0
0
0
0
0
10
0
% N
% Pro:
10
0
10
0
0
0
0
0
0
0
10
10
0
0
20
% P
% Gln:
0
10
0
0
0
10
0
0
60
10
0
0
0
0
0
% Q
% Arg:
0
0
0
20
0
0
0
0
0
50
0
0
0
0
0
% R
% Ser:
40
0
20
30
0
40
50
60
10
10
10
0
80
20
0
% S
% Thr:
10
10
0
0
20
0
10
10
10
10
40
20
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _