Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIK3 All Species: 13.03
Human Site: S1034 Identified Species: 28.67
UniProt: Q9Y2K2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2K2 NP_079440.2 1263 139980 S1034 H Q P A L M H S E S M E E D C
Chimpanzee Pan troglodytes XP_508771 1263 139874 S1034 H Q P A L M H S E S M E E D C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536563 1290 143819 S1061 H Q P A L M R S E S M E E E C
Cat Felis silvestris
Mouse Mus musculus Q6P4S6 1311 145765 S1083 H Q P P L M H S E S M E E D C
Rat Rattus norvegicus Q9R1U5 776 84890 Q548 A S P F L G S Q S A T P V L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517352 1230 134087 R1001 C P S P G F G R Q V P L M P S
Chicken Gallus gallus Q9IA88 798 88848 E570 L L P V S F Q E G R R A S D T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 Q958 Y G E M L L L Q Q L G Q A A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_569972 1398 149888 A1160 A T P L L L E A A A G G D M Y
Honey Bee Apis mellifera XP_395722 901 98876 P673 L A S P S H S P A S I P G S P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798437 1066 118092 A838 G S G S L H G A G S L E H V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 N.A. 89 N.A. 88.4 28.5 N.A. 70.9 29.5 N.A. 58.4 N.A. 26.9 32.2 N.A. 30.7
Protein Similarity: 100 99.8 N.A. 92.1 N.A. 91.7 40.6 N.A. 76.8 43.5 N.A. 69.6 N.A. 38.6 44.9 N.A. 46
P-Site Identity: 100 100 N.A. 86.6 N.A. 93.3 13.3 N.A. 0 13.3 N.A. 6.6 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 100 N.A. 93.3 N.A. 93.3 20 N.A. 6.6 13.3 N.A. 33.3 N.A. 40 13.3 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 28 0 0 0 19 19 19 0 10 10 10 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 37 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 10 37 0 % D
% Glu: 0 0 10 0 0 0 10 10 37 0 0 46 37 10 10 % E
% Phe: 0 0 0 10 0 19 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 0 10 10 19 0 19 0 19 10 10 0 10 % G
% His: 37 0 0 0 0 19 28 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 10 0 10 73 19 10 0 0 10 10 10 0 10 0 % L
% Met: 0 0 0 10 0 37 0 0 0 0 37 0 10 10 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 64 28 0 0 0 10 0 0 10 19 0 10 10 % P
% Gln: 0 37 0 0 0 0 10 19 19 0 0 10 0 0 10 % Q
% Arg: 0 0 0 0 0 0 10 10 0 10 10 0 0 0 0 % R
% Ser: 0 19 19 10 19 0 19 37 10 55 0 0 10 10 10 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 10 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 10 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _