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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK3
All Species:
16.06
Human Site:
S1198
Identified Species:
35.33
UniProt:
Q9Y2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K2
NP_079440.2
1263
139980
S1198
D
A
V
L
S
Q
S
S
L
M
G
S
Q
Q
F
Chimpanzee
Pan troglodytes
XP_508771
1263
139874
S1198
D
A
V
L
S
Q
S
S
L
M
G
S
Q
Q
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536563
1290
143819
S1225
D
A
V
L
S
Q
S
S
L
M
G
S
Q
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6P4S6
1311
145765
S1247
D
A
V
L
S
Q
S
S
L
M
G
S
Q
Q
F
Rat
Rattus norvegicus
Q9R1U5
776
84890
P712
L
L
Q
P
G
M
S
P
V
A
S
A
A
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517352
1230
134087
A1165
S
S
A
R
M
A
D
A
M
F
G
P
G
S
L
Chicken
Gallus gallus
Q9IA88
798
88848
V734
F
G
V
S
V
S
P
V
S
S
A
A
H
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S1122
L
L
A
G
K
A
L
S
S
A
R
M
S
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
S1324
A
A
P
N
G
A
G
S
G
G
S
A
A
G
V
Honey Bee
Apis mellifera
XP_395722
901
98876
K837
I
D
A
R
A
P
P
K
G
F
I
F
S
T
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798437
1066
118092
S1002
L
Q
N
A
A
P
T
S
I
S
N
E
V
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
89
N.A.
88.4
28.5
N.A.
70.9
29.5
N.A.
58.4
N.A.
26.9
32.2
N.A.
30.7
Protein Similarity:
100
99.8
N.A.
92.1
N.A.
91.7
40.6
N.A.
76.8
43.5
N.A.
69.6
N.A.
38.6
44.9
N.A.
46
P-Site Identity:
100
100
N.A.
100
N.A.
100
13.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
26.6
13.3
N.A.
6.6
N.A.
20
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
46
28
10
19
28
0
10
0
19
10
28
19
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
37
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
19
0
10
0
0
37
% F
% Gly:
0
10
0
10
19
0
10
0
19
10
46
0
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% I
% Lys:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
28
19
0
37
0
0
10
0
37
0
0
0
0
10
28
% L
% Met:
0
0
0
0
10
10
0
0
10
37
0
10
0
0
0
% M
% Asn:
0
0
10
10
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
10
0
19
19
10
0
0
0
10
0
10
0
% P
% Gln:
0
10
10
0
0
37
0
0
0
0
0
0
37
46
0
% Q
% Arg:
0
0
0
19
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
10
0
10
37
10
46
64
19
19
19
37
19
10
0
% S
% Thr:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% T
% Val:
0
0
46
0
10
0
0
10
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _