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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK3
All Species:
19.7
Human Site:
S562
Identified Species:
43.33
UniProt:
Q9Y2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K2
NP_079440.2
1263
139980
S562
H
L
P
T
E
R
F
S
P
V
R
R
F
S
D
Chimpanzee
Pan troglodytes
XP_508771
1263
139874
S562
H
L
P
T
E
R
F
S
P
V
R
R
F
S
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536563
1290
143819
S593
H
L
P
T
E
R
F
S
P
V
R
R
F
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6P4S6
1311
145765
S610
H
L
P
T
E
R
F
S
P
V
R
R
F
S
D
Rat
Rattus norvegicus
Q9R1U5
776
84890
I87
L
L
N
H
P
N
I
I
K
L
Y
Q
V
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517352
1230
134087
S516
H
L
P
A
E
R
F
S
P
V
R
R
F
S
D
Chicken
Gallus gallus
Q9IA88
798
88848
E109
T
E
F
A
K
N
G
E
M
F
D
H
L
T
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
M496
A
L
A
Q
M
Q
L
M
P
T
P
S
L
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
S678
S
E
F
I
I
K
Q
S
T
E
D
C
R
A
L
Honey Bee
Apis mellifera
XP_395722
901
98876
V212
D
V
W
S
L
G
V
V
L
Y
V
L
V
C
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798437
1066
118092
S377
D
S
D
P
E
E
P
S
P
E
A
L
A
R
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
89
N.A.
88.4
28.5
N.A.
70.9
29.5
N.A.
58.4
N.A.
26.9
32.2
N.A.
30.7
Protein Similarity:
100
99.8
N.A.
92.1
N.A.
91.7
40.6
N.A.
76.8
43.5
N.A.
69.6
N.A.
38.6
44.9
N.A.
46
P-Site Identity:
100
100
N.A.
100
N.A.
100
6.6
N.A.
93.3
0
N.A.
13.3
N.A.
6.6
0
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
100
26.6
N.A.
93.3
13.3
N.A.
20
N.A.
20
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
0
0
0
0
0
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
19
0
10
0
0
0
0
0
0
0
19
0
0
0
46
% D
% Glu:
0
19
0
0
55
10
0
10
0
19
0
0
0
0
10
% E
% Phe:
0
0
19
0
0
0
46
0
0
10
0
0
46
0
0
% F
% Gly:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
10
% G
% His:
46
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
10
0
10
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
64
0
0
10
0
10
0
10
10
0
19
19
0
10
% L
% Met:
0
0
0
0
10
0
0
10
10
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
46
10
10
0
10
0
64
0
10
0
0
0
10
% P
% Gln:
0
0
0
10
0
10
10
0
0
0
0
10
0
10
0
% Q
% Arg:
0
0
0
0
0
46
0
0
0
0
46
46
10
10
0
% R
% Ser:
10
10
0
10
0
0
0
64
0
0
0
10
0
46
10
% S
% Thr:
10
0
0
37
0
0
0
0
10
10
0
0
0
10
0
% T
% Val:
0
10
0
0
0
0
10
10
0
46
10
0
19
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _