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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK3
All Species:
17.88
Human Site:
S688
Identified Species:
39.33
UniProt:
Q9Y2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K2
NP_079440.2
1263
139980
S688
N
H
L
F
R
Q
P
S
N
S
P
P
P
M
S
Chimpanzee
Pan troglodytes
XP_508771
1263
139874
S688
N
H
L
F
R
Q
P
S
N
S
P
P
P
M
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536563
1290
143819
S719
N
H
L
F
R
P
P
S
N
S
P
P
P
M
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P4S6
1311
145765
S736
N
H
L
F
R
Q
P
S
N
S
P
P
P
V
S
Rat
Rattus norvegicus
Q9R1U5
776
84890
V212
L
D
I
W
S
L
G
V
V
L
Y
V
L
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517352
1230
134087
S642
N
H
L
F
R
Q
P
S
D
S
P
P
P
V
S
Chicken
Gallus gallus
Q9IA88
798
88848
R234
N
L
P
T
L
R
Q
R
V
L
E
G
R
F
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
L622
I
Q
A
Y
K
T
Q
L
E
N
N
S
L
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
K809
G
Q
E
T
N
D
A
K
S
N
G
D
S
R
S
Honey Bee
Apis mellifera
XP_395722
901
98876
L337
V
S
A
I
Y
N
L
L
V
D
R
L
E
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798437
1066
118092
G502
F
G
R
R
A
S
D
G
G
A
N
M
Y
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
89
N.A.
88.4
28.5
N.A.
70.9
29.5
N.A.
58.4
N.A.
26.9
32.2
N.A.
30.7
Protein Similarity:
100
99.8
N.A.
92.1
N.A.
91.7
40.6
N.A.
76.8
43.5
N.A.
69.6
N.A.
38.6
44.9
N.A.
46
P-Site Identity:
100
100
N.A.
93.3
N.A.
93.3
0
N.A.
86.6
6.6
N.A.
0
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
20
N.A.
100
13.3
N.A.
26.6
N.A.
20
6.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
0
10
0
10
0
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
10
10
0
10
10
0
10
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
0
10
0
10
0
0
% E
% Phe:
10
0
0
46
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
10
0
0
0
0
10
10
10
0
10
10
0
0
0
% G
% His:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
10
10
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
10
46
0
10
10
10
19
0
19
0
10
19
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
28
0
% M
% Asn:
55
0
0
0
10
10
0
0
37
19
19
0
0
0
10
% N
% Pro:
0
0
10
0
0
10
46
0
0
0
46
46
46
10
0
% P
% Gln:
0
19
0
0
0
37
19
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
46
10
0
10
0
0
10
0
10
10
19
% R
% Ser:
0
10
0
0
10
10
0
46
10
46
0
10
10
0
55
% S
% Thr:
0
0
0
19
0
10
0
0
0
0
0
0
0
0
10
% T
% Val:
10
0
0
0
0
0
0
10
28
0
0
10
0
28
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _