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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK3
All Species:
7.58
Human Site:
S771
Identified Species:
16.67
UniProt:
Q9Y2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K2
NP_079440.2
1263
139980
S771
P
G
T
A
A
G
S
S
G
R
G
I
S
I
S
Chimpanzee
Pan troglodytes
XP_508771
1263
139874
S771
P
G
T
A
A
G
S
S
G
R
G
I
S
I
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536563
1290
143819
A802
P
G
T
A
A
G
S
A
G
R
S
I
S
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6P4S6
1311
145765
A819
A
G
T
A
A
G
S
A
G
R
S
I
P
I
S
Rat
Rattus norvegicus
Q9R1U5
776
84890
Q295
D
D
P
A
F
S
M
Q
G
Y
T
S
N
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517352
1230
134087
R725
P
G
A
A
V
G
G
R
G
T
A
T
S
P
C
Chicken
Gallus gallus
Q9IA88
798
88848
D317
I
M
Q
T
L
G
I
D
R
Q
R
T
V
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
T705
Q
P
S
S
P
P
P
T
H
P
S
N
H
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
S892
M
R
S
Y
A
S
S
S
S
S
S
G
V
L
A
Honey Bee
Apis mellifera
XP_395722
901
98876
D420
S
Y
N
H
T
S
G
D
P
T
L
R
L
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798437
1066
118092
N585
I
G
P
D
V
L
T
N
N
D
M
P
L
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
89
N.A.
88.4
28.5
N.A.
70.9
29.5
N.A.
58.4
N.A.
26.9
32.2
N.A.
30.7
Protein Similarity:
100
99.8
N.A.
92.1
N.A.
91.7
40.6
N.A.
76.8
43.5
N.A.
69.6
N.A.
38.6
44.9
N.A.
46
P-Site Identity:
100
100
N.A.
86.6
N.A.
73.3
13.3
N.A.
40
13.3
N.A.
0
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
93.3
N.A.
80
26.6
N.A.
40
20
N.A.
26.6
N.A.
40
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
55
46
0
0
19
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
10
0
10
0
0
0
19
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
55
0
0
0
55
19
0
55
0
19
10
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
19
0
0
0
0
0
10
0
0
0
0
37
0
37
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
10
10
0
0
0
0
10
0
19
37
0
% L
% Met:
10
10
0
0
0
0
10
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
10
0
0
10
10
0
0
% N
% Pro:
37
10
19
0
10
10
10
0
10
10
0
10
10
10
10
% P
% Gln:
10
0
10
0
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
10
10
37
10
10
0
0
0
% R
% Ser:
10
0
19
10
0
28
46
28
10
10
37
10
37
0
55
% S
% Thr:
0
0
37
10
10
0
10
10
0
19
10
19
0
0
0
% T
% Val:
0
0
0
0
19
0
0
0
0
0
0
0
19
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _