KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIK3
All Species:
17.58
Human Site:
T616
Identified Species:
38.67
UniProt:
Q9Y2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K2
NP_079440.2
1263
139980
T616
D
E
R
T
L
E
K
T
Q
Q
Q
H
M
L
Y
Chimpanzee
Pan troglodytes
XP_508771
1263
139874
T616
D
E
R
T
L
E
K
T
Q
Q
Q
H
M
L
Y
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536563
1290
143819
T647
D
E
R
A
L
E
K
T
Q
Q
Q
H
M
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6P4S6
1311
145765
T664
D
E
R
T
L
E
K
T
Q
Q
Q
H
M
L
Y
Rat
Rattus norvegicus
Q9R1U5
776
84890
H141
L
S
A
V
E
Y
C
H
N
H
H
I
V
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517352
1230
134087
T570
D
E
R
V
L
E
K
T
Q
Q
Q
H
M
L
Y
Chicken
Gallus gallus
Q9IA88
798
88848
K163
L
D
A
N
M
N
I
K
L
A
D
F
G
F
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
R550
H
T
Q
Q
L
L
K
R
P
R
G
Q
S
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_569972
1398
149888
P732
E
S
G
S
A
P
C
P
G
E
I
N
G
K
T
Honey Bee
Apis mellifera
XP_395722
901
98876
L266
V
V
E
P
E
R
R
L
S
I
S
Q
I
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798437
1066
118092
E431
M
G
L
G
G
G
G
E
G
D
A
H
L
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
N.A.
89
N.A.
88.4
28.5
N.A.
70.9
29.5
N.A.
58.4
N.A.
26.9
32.2
N.A.
30.7
Protein Similarity:
100
99.8
N.A.
92.1
N.A.
91.7
40.6
N.A.
76.8
43.5
N.A.
69.6
N.A.
38.6
44.9
N.A.
46
P-Site Identity:
100
100
N.A.
93.3
N.A.
100
0
N.A.
93.3
0
N.A.
13.3
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
6.6
N.A.
93.3
13.3
N.A.
26.6
N.A.
26.6
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
10
0
0
0
0
10
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% C
% Asp:
46
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% D
% Glu:
10
46
10
0
19
46
0
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
0
10
10
10
10
10
10
0
19
0
10
0
19
0
19
% G
% His:
10
0
0
0
0
0
0
10
0
10
10
55
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
10
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
55
10
0
0
0
0
0
10
0
% K
% Leu:
19
0
10
0
55
10
0
10
10
0
0
0
10
55
10
% L
% Met:
10
0
0
0
10
0
0
0
0
0
0
0
46
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
10
0
0
10
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
10
10
0
0
0
0
10
0
% P
% Gln:
0
0
10
10
0
0
0
0
46
46
46
19
0
0
0
% Q
% Arg:
0
0
46
0
0
10
10
10
0
10
0
0
0
0
10
% R
% Ser:
0
19
0
10
0
0
0
0
10
0
10
0
10
0
0
% S
% Thr:
0
10
0
28
0
0
0
46
0
0
0
0
0
0
10
% T
% Val:
10
10
0
19
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
46
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _