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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STXBP5L All Species: 13.64
Human Site: S962 Identified Species: 30
UniProt: Q9Y2K9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2K9 NP_055795.1 1186 131887 S962 E K Q A K V F S L P S Q T C L
Chimpanzee Pan troglodytes XP_516678 1303 144261 S1079 E K Q A K V F S L P S Q T C L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533442 1260 139162 K1045 P T Q N C A Y K Q N I T E T S
Cat Felis silvestris
Mouse Mus musculus Q5DQR4 1185 131826 S961 E K Q A K V F S L P S Q T C L
Rat Rattus norvegicus Q9WU70 1152 127641 K937 P T Q N C A Y K Q N I T E T S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507080 1121 123964 Q907 T Q N C A Y K Q N I T E T S F
Chicken Gallus gallus XP_416550 1184 130501 S960 E K Q A K V F S L P S Q T C L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5SQE2 1159 128185 F938 S E R Q A K V F Y M P S Q A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08111 1161 126874 F942 N G V S S L C F T N S G E A L
Honey Bee Apis mellifera XP_391820 1090 120734 N876 C L V C Y V S N G H I A T Y S
Nematode Worm Caenorhab. elegans NP_491623 1124 123673 H909 L V K A T P T H I R G Y P C L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91 N.A. 61.3 N.A. 95.8 64.7 N.A. 64.3 87.4 N.A. 71.1 N.A. 22.3 42.4 35.8 N.A.
Protein Similarity: 100 91 N.A. 75.3 N.A. 98.7 79.1 N.A. 79.5 94.4 N.A. 83.9 N.A. 40.2 59.7 54.8 N.A.
P-Site Identity: 100 100 N.A. 6.6 N.A. 100 6.6 N.A. 6.6 100 N.A. 0 N.A. 13.3 13.3 20 N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 13.3 N.A. 26.6 100 N.A. 13.3 N.A. 26.6 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 46 19 19 0 0 0 0 0 10 0 19 0 % A
% Cys: 10 0 0 19 19 0 10 0 0 0 0 0 0 46 10 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 37 10 0 0 0 0 0 0 0 0 0 10 28 0 0 % E
% Phe: 0 0 0 0 0 0 37 19 0 0 0 0 0 0 10 % F
% Gly: 0 10 0 0 0 0 0 0 10 0 10 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 10 28 0 0 0 0 % I
% Lys: 0 37 10 0 37 10 10 19 0 0 0 0 0 0 0 % K
% Leu: 10 10 0 0 0 10 0 0 37 0 0 0 0 0 55 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 0 10 19 0 0 0 10 10 28 0 0 0 0 0 % N
% Pro: 19 0 0 0 0 10 0 0 0 37 10 0 10 0 0 % P
% Gln: 0 10 55 10 0 0 0 10 19 0 0 37 10 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % R
% Ser: 10 0 0 10 10 0 10 37 0 0 46 10 0 10 28 % S
% Thr: 10 19 0 0 10 0 10 0 10 0 10 19 55 19 0 % T
% Val: 0 10 19 0 0 46 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 19 0 10 0 0 10 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _