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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP5L
All Species:
15.76
Human Site:
Y688
Identified Species:
34.67
UniProt:
Q9Y2K9
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2K9
NP_055795.1
1186
131887
Y688
L
Y
R
S
S
D
L
Y
Q
R
Q
P
R
S
P
Chimpanzee
Pan troglodytes
XP_516678
1303
144261
Y805
L
Y
R
S
S
D
L
Y
Q
R
Q
P
R
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533442
1260
139162
G776
K
A
V
L
L
N
L
G
T
I
E
L
Y
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5DQR4
1185
131826
Y687
L
Y
R
S
S
D
L
Y
Q
R
Q
P
R
S
P
Rat
Rattus norvegicus
Q9WU70
1152
127641
S668
K
A
V
L
L
N
L
S
T
I
E
L
Y
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507080
1121
123964
I638
G
G
E
P
P
Q
Q
I
T
S
L
A
V
N
S
Chicken
Gallus gallus
XP_416550
1184
130501
Y686
L
Y
G
S
S
D
P
Y
Q
R
Q
P
R
S
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SQE2
1159
128185
Q668
L
A
V
V
D
Y
L
Q
K
T
I
L
L
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08111
1161
126874
S673
R
K
L
R
K
G
R
S
T
R
T
N
Q
S
N
Honey Bee
Apis mellifera
XP_391820
1090
120734
S607
T
A
L
S
L
N
S
S
Y
G
L
M
A
Y
G
Nematode Worm
Caenorhab. elegans
NP_491623
1124
123673
S640
T
Q
C
A
L
I
Y
S
W
T
T
N
E
L
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
N.A.
61.3
N.A.
95.8
64.7
N.A.
64.3
87.4
N.A.
71.1
N.A.
22.3
42.4
35.8
N.A.
Protein Similarity:
100
91
N.A.
75.3
N.A.
98.7
79.1
N.A.
79.5
94.4
N.A.
83.9
N.A.
40.2
59.7
54.8
N.A.
P-Site Identity:
100
100
N.A.
6.6
N.A.
100
6.6
N.A.
0
86.6
N.A.
13.3
N.A.
13.3
6.6
0
N.A.
P-Site Similarity:
100
100
N.A.
20
N.A.
100
20
N.A.
6.6
86.6
N.A.
20
N.A.
20
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
10
0
0
0
0
0
0
0
10
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
10
37
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
0
0
19
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
10
0
0
10
0
10
0
10
0
0
0
19
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
19
10
0
0
0
0
% I
% Lys:
19
10
0
0
10
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
46
0
19
19
37
0
55
0
0
0
19
28
10
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
0
0
28
0
0
0
0
0
19
0
10
10
% N
% Pro:
0
0
0
10
10
0
10
0
0
0
0
37
0
0
37
% P
% Gln:
0
10
0
0
0
10
10
10
37
0
37
0
10
0
0
% Q
% Arg:
10
0
28
10
0
0
10
0
0
46
0
0
37
0
0
% R
% Ser:
0
0
0
46
37
0
10
37
0
10
0
0
0
46
28
% S
% Thr:
19
0
0
0
0
0
0
0
37
19
19
0
0
0
0
% T
% Val:
0
0
28
10
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
37
0
0
0
10
10
37
10
0
0
0
19
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _