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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3
All Species:
36.36
Human Site:
S307
Identified Species:
50
UniProt:
Q9Y2L1
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L1
NP_001121698.1
958
109003
S307
S
Q
W
V
A
P
S
S
V
V
L
H
D
E
G
Chimpanzee
Pan troglodytes
XP_509678
958
109081
S307
S
Q
W
V
A
P
S
S
V
V
L
H
D
E
G
Rhesus Macaque
Macaca mulatta
XP_001083933
948
107719
S297
S
Q
W
V
A
P
S
S
V
V
L
Q
D
E
G
Dog
Lupus familis
XP_542610
1186
133310
S535
N
Q
W
V
A
P
S
S
V
V
L
H
D
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CSH3
958
108819
S307
S
Q
W
V
A
P
S
S
V
V
L
D
D
E
G
Rat
Rattus norvegicus
Q5U2P0
1054
120741
G291
A
R
N
R
S
I
H
G
D
V
V
V
V
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514554
966
109727
S315
N
Q
W
V
A
P
S
S
V
V
L
L
D
E
G
Chicken
Gallus gallus
XP_417016
963
109342
S310
D
E
W
V
A
P
S
S
V
V
L
Q
D
D
G
Frog
Xenopus laevis
Q6GN11
1040
119148
S298
A
V
E
L
L
P
K
S
E
W
K
G
R
T
G
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
V287
N
R
A
V
H
G
D
V
V
V
I
E
L
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651246
982
112164
E308
A
E
W
S
A
P
S
E
I
V
L
E
E
K
N
Honey Bee
Apis mellifera
XP_397381
980
112421
D283
N
Q
W
S
S
P
S
D
I
I
L
Q
D
E
E
Nematode Worm
Caenorhab. elegans
Q17632
961
108768
K308
D
Q
W
T
A
P
E
K
K
I
R
L
R
D
V
Sea Urchin
Strong. purpuratus
XP_787332
1412
160533
T435
S
Q
W
T
A
P
S
T
V
I
A
E
D
K
G
Poplar Tree
Populus trichocarpa
XP_002303419
935
105261
S295
D
Q
W
H
E
E
K
S
L
S
I
V
D
E
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565418
933
104978
A292
D
Q
W
Q
D
E
K
A
L
S
I
A
E
E
D
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
S331
S
E
W
K
A
P
S
S
I
V
L
D
S
E
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.1
73.6
N.A.
91.1
35.2
N.A.
86.4
81
35.3
33.1
N.A.
55
55
46
36.7
Protein Similarity:
100
99.7
96.7
77.7
N.A.
96.4
52.1
N.A.
93.3
90.4
53.6
52.9
N.A.
72.7
72
63.3
50.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
86.6
73.3
20
20
N.A.
40
46.6
26.6
60
P-Site Similarity:
100
100
93.3
100
N.A.
93.3
40
N.A.
93.3
86.6
33.3
40
N.A.
73.3
73.3
40
80
Percent
Protein Identity:
46.8
N.A.
N.A.
47.9
43.3
N.A.
Protein Similarity:
66.3
N.A.
N.A.
65.7
61.9
N.A.
P-Site Identity:
33.3
N.A.
N.A.
20
60
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
46.6
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
18
0
6
0
65
0
0
6
0
0
6
6
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
0
0
6
0
6
6
6
0
0
12
59
12
6
% D
% Glu:
0
18
6
0
6
12
6
6
6
0
0
18
12
65
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
6
0
6
0
0
0
6
0
0
53
% G
% His:
0
0
0
6
6
0
6
0
0
0
0
18
0
0
6
% H
% Ile:
0
0
0
0
0
6
0
0
18
18
18
0
0
0
0
% I
% Lys:
0
0
0
6
0
0
18
6
6
0
6
0
0
12
0
% K
% Leu:
0
0
0
6
6
0
0
0
12
0
59
12
6
6
6
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
24
0
6
0
0
0
0
0
0
0
0
0
0
0
6
% N
% Pro:
0
0
0
0
0
77
0
0
0
0
0
0
0
0
6
% P
% Gln:
0
65
0
6
0
0
0
0
0
0
0
18
0
0
0
% Q
% Arg:
0
12
0
6
0
0
0
0
0
0
6
0
12
0
0
% R
% Ser:
36
0
0
12
12
0
65
59
0
12
0
0
6
0
0
% S
% Thr:
0
0
0
12
0
0
0
6
0
0
0
0
0
6
0
% T
% Val:
0
6
0
48
0
0
0
6
53
65
6
12
6
0
6
% V
% Trp:
0
0
83
0
0
0
0
0
0
6
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _