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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3
All Species:
38.79
Human Site:
S697
Identified Species:
53.33
UniProt:
Q9Y2L1
Number Species:
16
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L1
NP_001121698.1
958
109003
S697
K
H
P
A
P
P
P
S
N
Y
E
I
L
V
K
Chimpanzee
Pan troglodytes
XP_509678
958
109081
S697
K
H
P
A
P
P
P
S
N
Y
E
I
L
V
K
Rhesus Macaque
Macaca mulatta
XP_001083933
948
107719
S687
K
H
P
A
P
P
P
S
N
Y
E
I
L
V
K
Dog
Lupus familis
XP_542610
1186
133310
S925
K
H
P
A
P
P
P
S
N
Y
E
I
L
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CSH3
958
108819
S697
K
H
P
A
P
P
P
S
N
Y
D
I
L
V
K
Rat
Rattus norvegicus
Q5U2P0
1054
120741
E715
Q
H
P
P
P
H
Q
E
F
F
S
E
L
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514554
966
109727
S705
K
H
P
A
P
P
P
S
N
Y
E
I
L
V
K
Chicken
Gallus gallus
XP_417016
963
109342
S700
K
H
P
A
P
P
P
S
N
Y
D
I
L
V
K
Frog
Xenopus laevis
Q6GN11
1040
119148
E707
L
H
P
P
P
R
Q
E
F
F
Q
E
L
K
E
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
E707
H
H
P
P
P
K
Q
E
F
F
N
H
L
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651246
982
112164
T704
R
H
P
R
P
P
P
T
N
F
D
P
L
V
K
Honey Bee
Apis mellifera
XP_397381
980
112421
S672
R
H
P
E
P
P
P
S
N
F
E
P
L
I
K
Nematode Worm
Caenorhab. elegans
Q17632
961
108768
E709
R
H
P
V
P
L
K
E
S
Y
K
P
L
V
E
Sea Urchin
Strong. purpuratus
XP_787332
1412
160533
S1142
R
H
P
V
P
P
L
S
N
F
E
P
I
I
K
Poplar Tree
Populus trichocarpa
XP_002303419
935
105261
R694
P
E
C
S
L
L
R
R
H
P
T
P
T
K
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565418
933
104978
R692
P
S
C
S
L
L
R
R
H
P
T
P
T
R
E
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
A756
T
A
M
L
R
R
H
A
A
P
P
S
T
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.1
73.6
N.A.
91.1
35.2
N.A.
86.4
81
35.3
33.1
N.A.
55
55
46
36.7
Protein Similarity:
100
99.7
96.7
77.7
N.A.
96.4
52.1
N.A.
93.3
90.4
53.6
52.9
N.A.
72.7
72
63.3
50.8
P-Site Identity:
100
100
100
100
N.A.
93.3
26.6
N.A.
100
93.3
26.6
26.6
N.A.
60
66.6
40
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
100
100
46.6
40
N.A.
86.6
86.6
66.6
80
Percent
Protein Identity:
46.8
N.A.
N.A.
47.9
43.3
N.A.
Protein Similarity:
66.3
N.A.
N.A.
65.7
61.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
42
0
0
0
6
6
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
18
0
0
0
6
% D
% Glu:
0
6
0
6
0
0
0
24
0
0
42
12
0
0
30
% E
% Phe:
0
0
0
0
0
0
0
0
18
36
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
6
83
0
0
0
6
6
0
12
0
0
6
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
42
6
18
0
% I
% Lys:
42
0
0
0
0
6
6
0
0
0
6
0
0
12
59
% K
% Leu:
6
0
0
6
12
18
6
0
0
0
0
0
77
0
0
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
59
0
6
0
0
6
0
% N
% Pro:
12
0
83
18
83
59
53
0
0
18
6
36
0
0
0
% P
% Gln:
6
0
0
0
0
0
18
0
0
0
6
0
0
0
0
% Q
% Arg:
24
0
0
6
6
12
12
12
0
0
0
0
0
12
0
% R
% Ser:
0
6
0
12
0
0
0
53
6
0
6
6
0
0
0
% S
% Thr:
6
0
0
0
0
0
0
6
0
0
12
0
18
0
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
0
53
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
48
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _