KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3
All Species:
22.73
Human Site:
S842
Identified Species:
31.25
UniProt:
Q9Y2L1
Number Species:
16
Phosphosite Substitution
Charge Score:
0.31
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L1
NP_001121698.1
958
109003
S842
H
T
Q
L
F
F
K
S
K
G
I
V
S
E
E
Chimpanzee
Pan troglodytes
XP_509678
958
109081
S842
H
T
Q
L
F
F
K
S
K
G
I
V
S
E
E
Rhesus Macaque
Macaca mulatta
XP_001083933
948
107719
S832
H
T
Q
L
F
F
K
S
K
G
I
V
S
E
E
Dog
Lupus familis
XP_542610
1186
133310
S1070
H
T
Q
L
F
F
K
S
K
G
I
V
S
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9CSH3
958
108819
S842
H
T
Q
L
F
F
K
S
K
G
I
V
S
E
E
Rat
Rattus norvegicus
Q5U2P0
1054
120741
D865
F
Q
C
M
Y
F
K
D
R
D
P
E
T
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514554
966
109727
N850
H
T
Q
L
F
F
K
N
K
G
I
V
N
E
E
Chicken
Gallus gallus
XP_417016
963
109342
T845
H
T
Q
L
F
F
K
T
K
G
V
V
N
E
D
Frog
Xenopus laevis
Q6GN11
1040
119148
D853
F
Q
C
M
F
F
K
D
K
D
P
D
S
D
Q
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
D857
F
Q
C
M
Y
F
R
D
K
D
S
H
T
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651246
982
112164
G851
N
T
H
L
F
F
R
G
K
E
E
D
E
E
G
Honey Bee
Apis mellifera
XP_397381
980
112421
E819
N
T
H
L
F
F
R
E
K
I
Q
D
E
E
G
Nematode Worm
Caenorhab. elegans
Q17632
961
108768
G856
N
V
V
R
Y
F
K
G
K
V
E
T
C
E
G
Sea Urchin
Strong. purpuratus
XP_787332
1412
160533
D1289
H
T
Q
I
F
F
K
D
K
T
V
D
E
D
G
Poplar Tree
Populus trichocarpa
XP_002303419
935
105261
Q830
N
Y
R
H
R
N
A
Q
M
A
S
R
G
S
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565418
933
104978
Q828
N
Y
R
H
R
N
A
Q
M
A
G
R
A
S
V
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
F893
R
K
H
R
N
A
Q
F
A
G
R
A
S
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.1
73.6
N.A.
91.1
35.2
N.A.
86.4
81
35.3
33.1
N.A.
55
55
46
36.7
Protein Similarity:
100
99.7
96.7
77.7
N.A.
96.4
52.1
N.A.
93.3
90.4
53.6
52.9
N.A.
72.7
72
63.3
50.8
P-Site Identity:
100
100
100
100
N.A.
100
26.6
N.A.
86.6
73.3
33.3
20
N.A.
40
40
26.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
53.3
N.A.
100
100
53.3
53.3
N.A.
53.3
53.3
40
66.6
Percent
Protein Identity:
46.8
N.A.
N.A.
47.9
43.3
N.A.
Protein Similarity:
66.3
N.A.
N.A.
65.7
61.9
N.A.
P-Site Identity:
0
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
6
12
0
6
12
0
6
6
0
0
% A
% Cys:
0
0
18
0
0
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
0
0
0
0
0
0
0
24
0
18
0
24
0
18
6
% D
% Glu:
0
0
0
0
0
0
0
6
0
6
12
6
18
65
53
% E
% Phe:
18
0
0
0
65
83
0
6
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
48
6
0
6
0
24
% G
% His:
48
0
18
12
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
0
6
0
0
0
0
0
6
36
0
0
6
0
% I
% Lys:
0
6
0
0
0
0
65
0
77
0
0
0
0
0
0
% K
% Leu:
0
0
0
53
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
18
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
30
0
0
0
6
12
0
6
0
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% P
% Gln:
0
18
48
0
0
0
6
12
0
0
6
0
0
0
6
% Q
% Arg:
6
0
12
12
12
0
18
0
6
0
6
12
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
30
0
0
12
0
42
12
0
% S
% Thr:
0
59
0
0
0
0
0
6
0
6
0
6
12
0
0
% T
% Val:
0
6
6
0
0
0
0
0
0
6
12
42
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
18
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _