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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3
All Species:
15.15
Human Site:
S926
Identified Species:
20.83
UniProt:
Q9Y2L1
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L1
NP_001121698.1
958
109003
S926
Q
H
Q
K
I
R
M
S
L
V
E
P
Q
I
P
Chimpanzee
Pan troglodytes
XP_509678
958
109081
S926
Q
H
Q
K
I
R
M
S
L
V
E
P
Q
I
P
Rhesus Macaque
Macaca mulatta
XP_001083933
948
107719
S916
Q
H
Q
K
I
R
M
S
L
V
E
P
Q
I
P
Dog
Lupus familis
XP_542610
1186
133310
S1154
Q
H
Q
K
I
R
M
S
L
V
E
P
Q
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CSH3
958
108819
A926
Q
H
Q
K
I
R
M
A
L
V
E
P
Q
I
P
Rat
Rattus norvegicus
Q5U2P0
1054
120741
V972
D
M
I
R
L
E
I
V
S
N
K
P
Y
M
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514554
966
109727
A934
Q
H
Q
K
I
R
M
A
L
V
E
P
Q
I
P
Chicken
Gallus gallus
XP_417016
963
109342
E929
Q
H
Q
K
I
R
M
E
L
V
E
P
K
I
L
Frog
Xenopus laevis
Q6GN11
1040
119148
I960
D
S
I
R
L
E
I
I
S
N
R
P
N
P
S
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
S1020
E
E
K
Q
F
R
Q
S
K
T
P
N
L
Y
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651246
982
112164
R943
Q
H
E
K
L
I
F
R
L
V
K
P
Y
I
K
Honey Bee
Apis mellifera
XP_397381
980
112421
K902
Q
H
E
K
L
I
F
K
L
V
K
P
F
I
S
Nematode Worm
Caenorhab. elegans
Q17632
961
108768
Q938
Q
R
P
R
V
E
L
Q
L
I
K
P
A
I
P
Sea Urchin
Strong. purpuratus
XP_787332
1412
160533
Q1374
Q
H
Q
K
L
R
L
Q
L
V
Q
P
E
V
P
Poplar Tree
Populus trichocarpa
XP_002303419
935
105261
Q912
S
V
S
Y
S
I
L
Q
A
V
K
I
H
L
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565418
933
104978
Q910
S
L
S
Y
S
V
L
Q
T
V
K
I
H
M
E
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
V975
D
K
P
R
D
V
Y
V
F
D
K
V
E
V
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.1
73.6
N.A.
91.1
35.2
N.A.
86.4
81
35.3
33.1
N.A.
55
55
46
36.7
Protein Similarity:
100
99.7
96.7
77.7
N.A.
96.4
52.1
N.A.
93.3
90.4
53.6
52.9
N.A.
72.7
72
63.3
50.8
P-Site Identity:
100
100
100
100
N.A.
93.3
6.6
N.A.
93.3
80
6.6
13.3
N.A.
46.6
46.6
33.3
60
P-Site Similarity:
100
100
100
100
N.A.
100
40
N.A.
100
86.6
26.6
33.3
N.A.
66.6
66.6
66.6
93.3
Percent
Protein Identity:
46.8
N.A.
N.A.
47.9
43.3
N.A.
Protein Similarity:
66.3
N.A.
N.A.
65.7
61.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
12
6
0
0
0
6
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
18
0
0
0
6
0
0
0
0
6
0
0
0
0
0
% D
% Glu:
6
6
12
0
0
18
0
6
0
0
42
0
12
0
12
% E
% Phe:
0
0
0
0
6
0
12
0
6
0
0
0
6
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
59
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
12
0
42
18
12
6
0
6
0
12
0
59
0
% I
% Lys:
0
6
6
59
0
0
0
6
6
0
42
0
6
0
6
% K
% Leu:
0
6
0
0
30
0
24
0
65
0
0
0
6
6
6
% L
% Met:
0
6
0
0
0
0
42
0
0
0
0
0
0
12
6
% M
% Asn:
0
0
0
0
0
0
0
0
0
12
0
6
6
0
0
% N
% Pro:
0
0
12
0
0
0
0
0
0
0
6
77
0
6
48
% P
% Gln:
65
0
48
6
0
0
6
24
0
0
6
0
36
0
6
% Q
% Arg:
0
6
0
24
0
53
0
6
0
0
6
0
0
0
0
% R
% Ser:
12
6
12
0
12
0
0
30
12
0
0
0
0
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
6
6
0
0
0
0
0
% T
% Val:
0
6
0
0
6
12
0
12
0
71
0
6
0
12
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
6
0
0
0
0
0
12
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _