KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3
All Species:
13.64
Human Site:
T113
Identified Species:
18.75
UniProt:
Q9Y2L1
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L1
NP_001121698.1
958
109003
T113
Y
K
R
I
R
D
V
T
N
N
Q
E
K
H
F
Chimpanzee
Pan troglodytes
XP_509678
958
109081
T113
Y
K
R
I
R
D
V
T
N
N
Q
E
K
H
F
Rhesus Macaque
Macaca mulatta
XP_001083933
948
107719
F110
V
S
T
D
F
L
L
F
R
F
F
L
S
F
S
Dog
Lupus familis
XP_542610
1186
133310
T341
Y
K
R
I
R
D
V
T
N
N
Q
E
K
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9CSH3
958
108819
T113
Y
K
R
I
R
D
V
T
N
N
Q
E
K
H
F
Rat
Rattus norvegicus
Q5U2P0
1054
120741
L107
Y
N
K
L
R
N
L
L
K
D
A
R
H
D
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514554
966
109727
I120
Y
K
R
I
R
D
V
I
N
N
F
E
K
H
F
Chicken
Gallus gallus
XP_417016
963
109342
I114
Y
K
R
I
R
D
V
I
G
N
P
E
K
H
F
Frog
Xenopus laevis
Q6GN11
1040
119148
L103
Y
K
K
L
C
S
L
L
R
D
T
R
H
D
C
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
L104
Y
N
R
L
R
S
L
L
K
D
P
R
H
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651246
982
112164
V111
Y
K
R
F
N
E
I
V
H
D
R
T
R
N
F
Honey Bee
Apis mellifera
XP_397381
980
112421
I96
Y
K
R
L
K
N
L
I
N
N
V
H
R
K
F
Nematode Worm
Caenorhab. elegans
Q17632
961
108768
C122
Y
K
K
M
N
S
L
C
Y
E
D
A
K
D
R
Sea Urchin
Strong. purpuratus
XP_787332
1412
160533
I238
Y
K
R
I
R
D
L
I
A
N
E
T
K
R
F
Poplar Tree
Populus trichocarpa
XP_002303419
935
105261
I102
Y
G
R
I
R
N
L
I
D
S
P
A
R
R
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565418
933
104978
C99
Y
N
R
I
R
L
L
C
S
N
P
A
R
Q
F
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
C136
Y
T
R
L
R
T
L
C
R
D
S
D
D
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.1
73.6
N.A.
91.1
35.2
N.A.
86.4
81
35.3
33.1
N.A.
55
55
46
36.7
Protein Similarity:
100
99.7
96.7
77.7
N.A.
96.4
52.1
N.A.
93.3
90.4
53.6
52.9
N.A.
72.7
72
63.3
50.8
P-Site Identity:
100
100
0
100
N.A.
100
13.3
N.A.
86.6
80
13.3
20
N.A.
26.6
40
20
60
P-Site Similarity:
100
100
6.6
100
N.A.
100
46.6
N.A.
86.6
80
40
40
N.A.
73.3
73.3
40
73.3
Percent
Protein Identity:
46.8
N.A.
N.A.
47.9
43.3
N.A.
Protein Similarity:
66.3
N.A.
N.A.
65.7
61.9
N.A.
P-Site Identity:
33.3
N.A.
N.A.
40
26.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
6
0
6
18
0
0
0
% A
% Cys:
0
0
0
0
6
0
0
18
0
0
0
0
0
0
18
% C
% Asp:
0
0
0
6
0
42
0
0
6
30
6
6
6
24
0
% D
% Glu:
0
0
0
0
0
6
0
0
0
6
6
36
0
0
0
% E
% Phe:
0
0
0
6
6
0
0
6
0
6
12
0
0
6
65
% F
% Gly:
0
6
0
0
0
0
0
0
6
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
6
0
0
6
18
42
0
% H
% Ile:
0
0
0
53
0
0
6
30
0
0
0
0
0
0
0
% I
% Lys:
0
65
18
0
6
0
0
0
12
0
0
0
48
6
6
% K
% Leu:
0
0
0
30
0
12
59
18
0
0
0
6
0
0
0
% L
% Met:
0
0
0
6
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
18
0
0
12
18
0
0
36
53
0
0
0
6
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
24
0
0
6
0
% Q
% Arg:
0
0
77
0
71
0
0
0
18
0
6
18
24
12
6
% R
% Ser:
0
6
0
0
0
18
0
0
6
6
6
0
6
0
6
% S
% Thr:
0
6
6
0
0
6
0
24
0
0
6
12
0
0
0
% T
% Val:
6
0
0
0
0
0
36
6
0
0
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
95
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _