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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DIS3
All Species:
28.86
Human Site:
T6
Identified Species:
39.68
UniProt:
Q9Y2L1
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L1
NP_001121698.1
958
109003
T6
_
_
M
L
K
S
K
T
F
L
K
K
T
R
A
Chimpanzee
Pan troglodytes
XP_509678
958
109081
T6
_
_
M
L
K
S
K
T
F
L
K
K
T
R
A
Rhesus Macaque
Macaca mulatta
XP_001083933
948
107719
T6
_
_
M
L
K
S
K
T
F
L
K
K
T
R
A
Dog
Lupus familis
XP_542610
1186
133310
T46
Y
P
T
P
L
T
Q
T
H
V
T
T
F
T
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9CSH3
958
108819
T6
_
_
M
L
R
S
K
T
F
L
K
K
T
R
A
Rat
Rattus norvegicus
Q5U2P0
1054
120741
V8
M
L
Q
K
R
E
K
V
L
L
L
R
T
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514554
966
109727
T6
_
_
M
L
K
S
R
T
F
L
K
K
T
R
T
Chicken
Gallus gallus
XP_417016
963
109342
T6
_
_
M
L
T
S
R
T
F
L
K
R
T
R
A
Frog
Xenopus laevis
Q6GN11
1040
119148
I7
_
M
L
K
T
E
K
I
L
H
L
K
T
Q
R
Zebra Danio
Brachydanio rerio
A2RV18
1057
120333
I7
_
M
I
K
T
E
K
I
L
H
L
N
S
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651246
982
112164
E6
_
_
M
Q
T
L
R
E
F
T
R
K
T
K
R
Honey Bee
Apis mellifera
XP_397381
980
112421
I6
_
_
M
L
T
T
K
I
F
F
R
K
T
K
G
Nematode Worm
Caenorhab. elegans
Q17632
961
108768
T17
I
H
S
V
A
L
H
T
T
Y
F
Q
N
R
S
Sea Urchin
Strong. purpuratus
XP_787332
1412
160533
N80
K
I
L
K
R
A
N
N
D
M
E
Q
Y
S
R
Poplar Tree
Populus trichocarpa
XP_002303419
935
105261
T6
_
_
M
L
H
S
K
T
F
N
K
K
T
R
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565418
933
104978
V6
_
_
M
L
Q
S
K
V
F
N
K
K
T
R
G
Baker's Yeast
Sacchar. cerevisiae
Q08162
1001
113688
K22
D
G
L
S
V
T
Q
K
V
F
V
R
S
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
95.1
73.6
N.A.
91.1
35.2
N.A.
86.4
81
35.3
33.1
N.A.
55
55
46
36.7
Protein Similarity:
100
99.7
96.7
77.7
N.A.
96.4
52.1
N.A.
93.3
90.4
53.6
52.9
N.A.
72.7
72
63.3
50.8
P-Site Identity:
100
100
100
6.6
N.A.
92.3
20
N.A.
84.6
76.9
21.4
7.1
N.A.
30.7
46.1
13.3
0
P-Site Similarity:
100
100
100
33.3
N.A.
100
33.3
N.A.
92.3
92.3
35.7
21.4
N.A.
53.8
69.2
40
46.6
Percent
Protein Identity:
46.8
N.A.
N.A.
47.9
43.3
N.A.
Protein Similarity:
66.3
N.A.
N.A.
65.7
61.9
N.A.
P-Site Identity:
76.9
N.A.
N.A.
69.2
6.6
N.A.
P-Site Similarity:
76.9
N.A.
N.A.
76.9
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
6
6
0
0
0
0
0
0
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
6
0
0
0
0
0
0
0
6
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
18
0
6
0
0
6
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
59
12
6
0
6
6
0
% F
% Gly:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
18
% G
% His:
0
6
0
0
6
0
6
0
6
12
0
0
0
0
0
% H
% Ile:
6
6
6
0
0
0
0
18
0
0
0
0
0
0
6
% I
% Lys:
6
0
0
24
24
0
59
6
0
0
48
59
0
12
6
% K
% Leu:
0
6
18
53
6
12
0
0
18
42
18
0
0
0
0
% L
% Met:
6
12
59
0
0
0
0
0
0
6
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
6
6
0
12
0
6
6
0
6
% N
% Pro:
0
6
0
6
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
6
6
6
0
12
0
0
0
0
12
0
6
6
% Q
% Arg:
0
0
0
0
18
0
18
0
0
0
12
18
0
59
18
% R
% Ser:
0
0
6
6
0
48
0
0
0
0
0
0
12
12
6
% S
% Thr:
0
0
6
0
30
18
0
53
6
6
6
6
71
6
6
% T
% Val:
0
0
0
6
6
0
0
12
6
6
6
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
6
0
0
0
0
0
0
0
0
6
0
0
6
0
0
% Y
% Spaces:
71
59
0
0
0
0
0
0
0
0
0
0
0
0
0
% _