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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1012 All Species: 17.58
Human Site: Y650 Identified Species: 48.33
UniProt: Q9Y2L5 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2L5 NP_055754.2 1435 160941 Y650 L R E Y L Y V Y K N V S Q L S
Chimpanzee Pan troglodytes XP_001159900 1435 160893 Y650 L R E Y L Y V Y K N V S Q L S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537289 1433 160646 Y650 L R E Y L Y V Y K N V S Q L S
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus NP_001099630 1433 160332 Y650 L R E Y L Y V Y K N V N Q L S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515270 1078 120406 A332 P A E G E K Q A A T H V S L D
Chicken Gallus gallus
Frog Xenopus laevis NP_001085189 1446 161543 Y649 L R E Y L F V Y K N V C Q Q S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649135 1319 147666 N573 F H I V L A G N R Y S R A G Q
Honey Bee Apis mellifera XP_395570 1294 146835 L548 E C L K G R N L Y G E A A K Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785733 1203 133420 R457 L S D H D R L R I F M H E F V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 96.3 N.A. N.A. 91 N.A. 66.1 N.A. 76.5 N.A. N.A. 29.1 33 N.A. 34.5
Protein Similarity: 100 99.6 N.A. 98.1 N.A. N.A. 95.9 N.A. 70.9 N.A. 86.5 N.A. N.A. 47.6 51.9 N.A. 50.6
P-Site Identity: 100 100 N.A. 100 N.A. N.A. 93.3 N.A. 13.3 N.A. 80 N.A. N.A. 6.6 0 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. N.A. 100 N.A. 13.3 N.A. 86.6 N.A. N.A. 13.3 6.6 N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 0 12 0 12 12 0 0 12 23 0 0 % A
% Cys: 0 12 0 0 0 0 0 0 0 0 0 12 0 0 0 % C
% Asp: 0 0 12 0 12 0 0 0 0 0 0 0 0 0 12 % D
% Glu: 12 0 67 0 12 0 0 0 0 0 12 0 12 0 0 % E
% Phe: 12 0 0 0 0 12 0 0 0 12 0 0 0 12 0 % F
% Gly: 0 0 0 12 12 0 12 0 0 12 0 0 0 12 0 % G
% His: 0 12 0 12 0 0 0 0 0 0 12 12 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 12 0 0 0 0 0 0 % I
% Lys: 0 0 0 12 0 12 0 0 56 0 0 0 0 12 0 % K
% Leu: 67 0 12 0 67 0 12 12 0 0 0 0 0 56 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 12 0 56 0 12 0 0 0 % N
% Pro: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 12 0 0 0 0 0 56 12 23 % Q
% Arg: 0 56 0 0 0 23 0 12 12 0 0 12 0 0 0 % R
% Ser: 0 12 0 0 0 0 0 0 0 0 12 34 12 0 56 % S
% Thr: 0 0 0 0 0 0 0 0 0 12 0 0 0 0 0 % T
% Val: 0 0 0 12 0 0 56 0 0 0 56 12 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 56 0 45 0 56 12 12 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _