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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4B
All Species:
22.12
Human Site:
S585
Identified Species:
54.07
UniProt:
Q9Y2L6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L6
NP_055938.1
980
111630
S585
Q
F
V
D
T
R
Q
S
R
E
M
L
S
T
H
Chimpanzee
Pan troglodytes
XP_516575
1268
142846
S873
Q
F
V
D
T
R
Q
S
R
E
M
L
S
T
H
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
S787
Q
F
V
D
T
R
Q
S
R
E
M
L
S
T
H
Dog
Lupus familis
XP_541808
1260
142030
S865
Q
F
V
D
T
R
Q
S
R
E
M
L
S
T
H
Cat
Felis silvestris
Mouse
Mus musculus
Q920B0
981
111548
S586
Q
F
M
D
T
R
H
S
R
E
M
L
S
T
H
Rat
Rattus norvegicus
P31977
586
69372
K193
S
A
M
L
E
Y
L
K
I
A
Q
D
L
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
S475
Q
F
L
E
T
R
Q
S
R
E
M
L
S
A
H
Chicken
Gallus gallus
Q9PU45
583
68536
E190
L
R
E
D
S
M
M
E
Y
L
K
I
A
Q
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
D242
L
N
I
Y
D
E
R
D
K
L
T
P
K
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
L652
E
P
Q
W
R
E
R
L
H
Q
S
H
H
Q
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
81.6
73.8
N.A.
93.2
20.7
N.A.
75.5
21.4
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
33.4
Protein Similarity:
100
77.1
82.4
76
N.A.
96.4
36.6
N.A.
81.2
37
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
100
N.A.
86.6
0
N.A.
80
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
93.3
26.6
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
10
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
60
10
0
0
10
0
0
0
10
0
0
10
% D
% Glu:
10
0
10
10
10
20
0
10
0
60
0
0
0
10
0
% E
% Phe:
0
60
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
10
0
10
0
0
10
10
0
60
% H
% Ile:
0
0
10
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
10
0
10
0
10
0
0
% K
% Leu:
20
0
10
10
0
0
10
10
0
20
0
60
10
0
0
% L
% Met:
0
0
20
0
0
10
10
0
0
0
60
0
0
0
10
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% P
% Gln:
60
0
10
0
0
0
50
0
0
10
10
0
0
20
10
% Q
% Arg:
0
10
0
0
10
60
20
0
60
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
0
60
0
0
10
0
60
0
0
% S
% Thr:
0
0
0
0
60
0
0
0
0
0
10
0
0
60
10
% T
% Val:
0
0
40
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
10
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _