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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD4B
All Species:
20.91
Human Site:
T690
Identified Species:
51.11
UniProt:
Q9Y2L6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2L6
NP_055938.1
980
111630
T690
S
T
E
Y
Y
C
V
T
P
V
T
G
P
Y
Y
Chimpanzee
Pan troglodytes
XP_516575
1268
142846
T978
S
T
E
Y
Y
C
V
T
P
V
T
G
P
Y
Y
Rhesus Macaque
Macaca mulatta
XP_001086554
1182
133673
T892
S
T
E
Y
Y
C
V
T
P
V
T
G
P
Y
Y
Dog
Lupus familis
XP_541808
1260
142030
T970
S
T
E
Y
Y
C
V
T
P
V
A
G
P
Y
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q920B0
981
111548
T691
S
S
E
Y
Y
C
V
T
P
A
A
S
P
Y
Y
Rat
Rattus norvegicus
P31977
586
69372
D298
Y
M
R
R
R
K
P
D
T
I
E
V
Q
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510163
868
98664
T580
S
A
E
Y
Y
C
A
T
P
S
A
G
S
Y
C
Chicken
Gallus gallus
Q9PU45
583
68536
R295
H
E
L
Y
M
R
R
R
K
P
D
T
I
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24564
635
74474
R347
R
E
K
A
E
H
E
R
Y
E
L
E
K
S
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786842
1120
127484
S757
S
N
H
I
S
R
T
S
P
R
R
G
K
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
76.7
81.6
73.8
N.A.
93.2
20.7
N.A.
75.5
21.4
N.A.
N.A.
N.A.
20.4
N.A.
N.A.
33.4
Protein Similarity:
100
77.1
82.4
76
N.A.
96.4
36.6
N.A.
81.2
37
N.A.
N.A.
N.A.
37.5
N.A.
N.A.
50.8
P-Site Identity:
100
100
100
93.3
N.A.
73.3
0
N.A.
60
6.6
N.A.
N.A.
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
80
6.6
N.A.
60
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
10
0
0
10
30
0
0
0
0
% A
% Cys:
0
0
0
0
0
60
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
20
60
0
10
0
10
0
0
10
10
10
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
60
0
0
0
% G
% His:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
10
0
0
10
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
10
0
0
0
20
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% L
% Met:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
20
% M
% Asn:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
70
10
0
0
50
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% Q
% Arg:
10
0
10
10
10
20
10
20
0
10
10
0
0
0
0
% R
% Ser:
70
10
0
0
10
0
0
10
0
10
0
10
10
10
0
% S
% Thr:
0
40
0
0
0
0
10
60
10
0
30
10
0
0
0
% T
% Val:
0
0
0
0
0
0
50
0
0
40
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
70
60
0
0
0
10
0
0
0
0
60
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _