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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL20 All Species: 29.7
Human Site: S352 Identified Species: 50.26
UniProt: Q9Y2M5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2M5 NP_055273.2 609 67955 S352 W R M V A S M S K R R C G V G
Chimpanzee Pan troglodytes XP_001149345 684 76181 S427 W R M V A S M S K R R C G V G
Rhesus Macaque Macaca mulatta XP_001097033 497 55038 V246 M S K R R C G V G V S V L D D
Dog Lupus familis XP_861742 531 58771 G279 S M S K R R C G V G V S V L D
Cat Felis silvestris
Mouse Mus musculus Q8VCK5 604 67393 S347 W R M V A S M S K R R C G V G
Rat Rattus norvegicus Q8K430 640 69714 M373 R W H V V A S M S T R R A R V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515196 722 79884 S465 W R M V A S M S K R R C G V G
Chicken Gallus gallus NP_001026500 610 68006 S353 W R M V A S M S K R R C G V G
Frog Xenopus laevis Q6NRH0 564 63190 T312 W S V L P S I T R K R R Y V A
Zebra Danio Brachydanio rerio Q5U374 564 62914 A312 W S F L P N I A R K R R Y V A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 S356 W K M V A P M S K R R C G V G
Honey Bee Apis mellifera XP_397065 620 68991 S363 W K M V A P M S K R R C G V G
Nematode Worm Caenorhab. elegans NP_491322 531 58629 K279 R D L V D E A K N Y L L L P V
Sea Urchin Strong. purpuratus XP_789626 583 65095 C326 W R M V A P M C K R R C G V G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89 73.7 87.1 N.A. 99.1 45.1 N.A. 83.9 98.8 41.3 41.3 N.A. 75.2 76.2 51.7 78
Protein Similarity: 100 89 76.1 87.1 N.A. 99.1 61.7 N.A. 84.3 99.3 59.4 58.1 N.A. 83.6 85.6 64.6 87.5
P-Site Identity: 100 100 0 0 N.A. 100 13.3 N.A. 100 100 26.6 20 N.A. 86.6 86.6 6.6 86.6
P-Site Similarity: 100 100 0 6.6 N.A. 100 20 N.A. 100 100 66.6 60 N.A. 93.3 93.3 13.3 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 58 8 8 8 0 0 0 0 8 0 15 % A
% Cys: 0 0 0 0 0 8 8 8 0 0 0 58 0 0 0 % C
% Asp: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 15 % D
% Glu: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 8 8 8 0 0 58 0 58 % G
% His: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 15 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 8 8 0 0 0 8 58 15 0 0 0 0 0 % K
% Leu: 0 0 8 15 0 0 0 0 0 0 8 8 15 8 0 % L
% Met: 8 8 58 0 0 0 58 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 15 22 0 0 0 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 15 43 0 8 15 8 0 0 15 58 79 22 0 8 0 % R
% Ser: 8 22 8 0 0 43 8 50 8 0 8 8 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % T
% Val: 0 0 8 72 8 0 0 8 8 8 8 8 8 72 15 % V
% Trp: 72 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _