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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL20
All Species:
22.73
Human Site:
S445
Identified Species:
38.46
UniProt:
Q9Y2M5
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2M5
NP_055273.2
609
67955
S445
N
K
W
T
R
V
A
S
M
S
T
R
R
L
G
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
S520
N
K
W
T
R
V
A
S
M
S
T
R
R
L
G
Rhesus Macaque
Macaca mulatta
XP_001097033
497
55038
L339
A
S
M
S
T
R
R
L
G
V
A
V
A
V
L
Dog
Lupus familis
XP_861742
531
58771
R372
V
A
S
M
S
T
R
R
L
G
V
A
V
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
S440
N
K
W
T
R
V
A
S
M
S
T
R
R
L
G
Rat
Rattus norvegicus
Q8K430
640
69714
A466
G
T
W
T
S
I
A
A
M
S
T
R
R
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
S558
N
K
W
T
R
V
A
S
M
S
T
R
R
L
G
Chicken
Gallus gallus
NP_001026500
610
68006
S446
N
K
W
T
R
V
A
S
M
S
T
R
R
L
G
Frog
Xenopus laevis
Q6NRH0
564
63190
L405
N
I
D
Q
W
S
M
L
G
D
M
Q
T
A
R
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
L405
N
I
D
Q
W
S
M
L
G
D
M
Q
T
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
P449
N
K
W
S
K
V
A
P
M
T
T
R
R
L
G
Honey Bee
Apis mellifera
XP_397065
620
68991
P456
N
K
W
S
K
V
S
P
M
T
T
R
R
L
G
Nematode Worm
Caenorhab. elegans
NP_491322
531
58629
I372
G
Q
S
Y
L
N
S
I
E
R
Y
D
P
M
T
Sea Urchin
Strong. purpuratus
XP_789626
583
65095
S419
N
R
W
T
R
V
A
S
M
S
T
R
R
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
73.7
87.1
N.A.
99.1
45.1
N.A.
83.9
98.8
41.3
41.3
N.A.
75.2
76.2
51.7
78
Protein Similarity:
100
89
76.1
87.1
N.A.
99.1
61.7
N.A.
84.3
99.3
59.4
58.1
N.A.
83.6
85.6
64.6
87.5
P-Site Identity:
100
100
0
0
N.A.
100
53.3
N.A.
100
100
6.6
6.6
N.A.
73.3
66.6
0
93.3
P-Site Similarity:
100
100
13.3
6.6
N.A.
100
66.6
N.A.
100
100
13.3
13.3
N.A.
93.3
93.3
20
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
0
58
8
0
0
8
8
8
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
0
0
0
0
0
15
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
22
8
0
0
0
0
58
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
15
0
0
0
8
0
8
0
0
0
0
0
0
0
% I
% Lys:
0
50
0
0
15
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
22
8
0
0
0
0
58
8
% L
% Met:
0
0
8
8
0
0
15
0
65
0
15
0
0
8
0
% M
% Asn:
72
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
15
0
0
0
0
8
0
0
% P
% Gln:
0
8
0
15
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
8
0
0
43
8
15
8
0
8
0
65
65
8
15
% R
% Ser:
0
8
15
22
15
15
15
43
0
50
0
0
0
0
0
% S
% Thr:
0
8
0
50
8
8
0
0
0
15
65
0
15
0
8
% T
% Val:
8
0
0
0
0
58
0
0
0
8
8
8
8
8
8
% V
% Trp:
0
0
65
0
15
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _