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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLHL20 All Species: 34.55
Human Site: S447 Identified Species: 58.46
UniProt: Q9Y2M5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2M5 NP_055273.2 609 67955 S447 W T R V A S M S T R R L G V A
Chimpanzee Pan troglodytes XP_001149345 684 76181 S522 W T R V A S M S T R R L G V A
Rhesus Macaque Macaca mulatta XP_001097033 497 55038 V341 M S T R R L G V A V A V L G G
Dog Lupus familis XP_861742 531 58771 G374 S M S T R R L G V A V A V L G
Cat Felis silvestris
Mouse Mus musculus Q8VCK5 604 67393 S442 W T R V A S M S T R R L G V A
Rat Rattus norvegicus Q8K430 640 69714 S468 W T S I A A M S T R R R Y V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515196 722 79884 S560 W T R V A S M S T R R L G V A
Chicken Gallus gallus NP_001026500 610 68006 S448 W T R V A S M S T R R L G V A
Frog Xenopus laevis Q6NRH0 564 63190 D407 D Q W S M L G D M Q T A R E G
Zebra Danio Brachydanio rerio Q5U374 564 62914 D407 D Q W S M L G D M Q T A R E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VUU5 623 68905 T451 W S K V A P M T T R R L G V A
Honey Bee Apis mellifera XP_397065 620 68991 T458 W S K V S P M T T R R L G V A
Nematode Worm Caenorhab. elegans NP_491322 531 58629 R374 S Y L N S I E R Y D P M T N Q
Sea Urchin Strong. purpuratus XP_789626 583 65095 S421 W T R V A S M S T R R L G V A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89 73.7 87.1 N.A. 99.1 45.1 N.A. 83.9 98.8 41.3 41.3 N.A. 75.2 76.2 51.7 78
Protein Similarity: 100 89 76.1 87.1 N.A. 99.1 61.7 N.A. 84.3 99.3 59.4 58.1 N.A. 83.6 85.6 64.6 87.5
P-Site Identity: 100 100 0 0 N.A. 100 60 N.A. 100 100 0 0 N.A. 73.3 66.6 0 100
P-Site Similarity: 100 100 13.3 13.3 N.A. 100 73.3 N.A. 100 100 6.6 6.6 N.A. 93.3 93.3 13.3 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 58 8 0 0 8 8 8 22 0 0 58 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 0 0 15 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 0 15 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 22 8 0 0 0 0 58 8 29 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 8 0 0 22 8 0 0 0 0 58 8 8 0 % L
% Met: 8 8 0 0 15 0 65 0 15 0 0 8 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 0 15 0 0 0 0 8 0 0 0 0 % P
% Gln: 0 15 0 0 0 0 0 0 0 15 0 0 0 0 8 % Q
% Arg: 0 0 43 8 15 8 0 8 0 65 65 8 15 0 8 % R
% Ser: 15 22 15 15 15 43 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 50 8 8 0 0 0 15 65 0 15 0 8 0 0 % T
% Val: 0 0 0 58 0 0 0 8 8 8 8 8 8 65 0 % V
% Trp: 65 0 15 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 8 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _