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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL20
All Species:
18.48
Human Site:
T489
Identified Species:
31.28
UniProt:
Q9Y2M5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2M5
NP_055273.2
609
67955
T489
P
Q
E
N
R
W
H
T
I
A
P
M
G
T
R
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
T564
P
Q
E
N
R
W
H
T
I
A
P
M
G
T
R
Rhesus Macaque
Macaca mulatta
XP_001097033
497
55038
T383
H
T
I
A
P
M
G
T
R
R
K
H
L
G
C
Dog
Lupus familis
XP_861742
531
58771
G416
W
H
T
I
A
P
M
G
T
R
R
K
H
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
T484
P
Q
E
N
R
W
H
T
I
A
P
M
G
T
R
Rat
Rattus norvegicus
Q8K430
640
69714
P510
P
Q
V
N
S
W
T
P
V
A
S
M
L
S
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
T602
P
Q
E
N
R
W
H
T
I
A
P
M
G
T
R
Chicken
Gallus gallus
NP_001026500
610
68006
T490
P
Q
E
N
R
W
H
T
I
A
P
M
G
T
R
Frog
Xenopus laevis
Q6NRH0
564
63190
W449
Y
D
P
H
T
G
H
W
S
H
V
T
P
M
A
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
W449
Y
D
P
H
T
G
H
W
T
S
V
T
P
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
A493
P
R
H
N
K
W
V
A
V
S
P
M
S
T
R
Honey Bee
Apis mellifera
XP_397065
620
68991
Q500
P
R
Q
N
K
W
S
Q
V
S
P
M
S
T
R
Nematode Worm
Caenorhab. elegans
NP_491322
531
58629
C416
G
G
Q
D
G
E
S
C
L
D
V
V
E
K
Y
Sea Urchin
Strong. purpuratus
XP_789626
583
65095
P463
P
R
T
N
K
W
T
P
V
A
P
M
G
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
73.7
87.1
N.A.
99.1
45.1
N.A.
83.9
98.8
41.3
41.3
N.A.
75.2
76.2
51.7
78
Protein Similarity:
100
89
76.1
87.1
N.A.
99.1
61.7
N.A.
84.3
99.3
59.4
58.1
N.A.
83.6
85.6
64.6
87.5
P-Site Identity:
100
100
6.6
0
N.A.
100
46.6
N.A.
100
100
6.6
6.6
N.A.
46.6
46.6
0
53.3
P-Site Similarity:
100
100
6.6
0
N.A.
100
60
N.A.
100
100
13.3
20
N.A.
73.3
80
26.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
0
50
0
0
0
0
15
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% C
% Asp:
0
15
0
8
0
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
36
0
0
8
0
0
0
0
0
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
8
15
8
8
0
0
0
0
43
8
8
% G
% His:
8
8
8
15
0
0
50
0
0
8
0
8
8
0
0
% H
% Ile:
0
0
8
8
0
0
0
0
36
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
22
0
0
0
0
0
8
8
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
0
15
8
0
% L
% Met:
0
0
0
0
0
8
8
0
0
0
0
65
0
15
0
% M
% Asn:
0
0
0
65
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
65
0
15
0
8
8
0
15
0
0
58
0
15
0
0
% P
% Gln:
0
43
15
0
0
0
0
8
0
0
0
0
0
0
0
% Q
% Arg:
0
22
0
0
36
0
0
0
8
15
8
0
0
0
58
% R
% Ser:
0
0
0
0
8
0
15
0
8
22
8
0
15
8
0
% S
% Thr:
0
8
15
0
15
0
15
43
15
0
0
15
0
58
0
% T
% Val:
0
0
8
0
0
0
8
0
29
0
22
8
0
0
0
% V
% Trp:
8
0
0
0
0
65
0
15
0
0
0
0
0
0
0
% W
% Tyr:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _