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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL20
All Species:
23.33
Human Site:
Y584
Identified Species:
39.49
UniProt:
Q9Y2M5
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2M5
NP_055273.2
609
67955
Y584
D
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
Chimpanzee
Pan troglodytes
XP_001149345
684
76181
Y659
D
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
Rhesus Macaque
Macaca mulatta
XP_001097033
497
55038
G473
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
L
Dog
Lupus familis
XP_861742
531
58771
Y506
D
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCK5
604
67393
Y579
D
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
Rat
Rattus norvegicus
Q8K430
640
69714
A605
R
T
N
K
W
V
A
A
S
C
M
F
T
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515196
722
79884
Y697
D
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
Chicken
Gallus gallus
NP_001026500
610
68006
Y585
D
A
N
T
W
R
L
Y
G
G
M
N
Y
R
R
Frog
Xenopus laevis
Q6NRH0
564
63190
I540
V
E
C
Y
D
P
L
I
D
S
W
A
V
V
T
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
V539
S
I
E
C
Y
D
P
V
I
D
S
W
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
C588
E
T
N
Q
W
R
L
C
G
C
M
N
Y
R
R
Honey Bee
Apis mellifera
XP_397065
620
68991
C595
E
Q
N
Q
W
K
L
C
G
C
M
N
Y
R
R
Nematode Worm
Caenorhab. elegans
NP_491322
531
58629
T507
Y
A
V
G
G
R
D
T
T
T
E
L
N
T
A
Sea Urchin
Strong. purpuratus
XP_789626
583
65095
C558
D
T
K
S
W
R
M
C
G
S
M
N
Y
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89
73.7
87.1
N.A.
99.1
45.1
N.A.
83.9
98.8
41.3
41.3
N.A.
75.2
76.2
51.7
78
Protein Similarity:
100
89
76.1
87.1
N.A.
99.1
61.7
N.A.
84.3
99.3
59.4
58.1
N.A.
83.6
85.6
64.6
87.5
P-Site Identity:
100
100
13.3
100
N.A.
100
33.3
N.A.
100
100
6.6
0
N.A.
66.6
60
13.3
60
P-Site Similarity:
100
100
13.3
100
N.A.
100
33.3
N.A.
100
100
6.6
6.6
N.A.
73.3
73.3
13.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
50
0
0
0
0
8
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
8
8
0
0
0
22
0
22
0
0
0
0
0
% C
% Asp:
50
0
0
0
8
8
8
0
8
8
0
0
0
0
0
% D
% Glu:
15
8
8
0
0
0
0
0
0
0
8
0
8
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
8
8
0
0
8
72
43
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
0
0
8
8
0
8
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
65
0
0
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
8
0
0
8
72
0
0
0
0
% M
% Asn:
0
8
65
0
0
0
0
0
0
0
8
65
8
0
0
% N
% Pro:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
15
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
8
65
0
0
0
0
0
0
8
79
72
% R
% Ser:
8
0
0
8
0
0
0
0
8
15
8
0
0
0
0
% S
% Thr:
0
22
8
43
0
0
0
8
8
8
0
0
8
8
8
% T
% Val:
8
0
8
0
0
8
0
8
0
0
0
0
8
15
8
% V
% Trp:
0
0
0
8
72
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
8
0
0
8
8
0
8
43
0
0
0
8
65
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _