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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIF3A
All Species:
10.61
Human Site:
S595
Identified Species:
25.93
UniProt:
Q9Y2N7
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2N7
NP_071907.3
669
72433
S595
G
V
R
P
P
K
R
S
P
S
P
E
H
E
N
Chimpanzee
Pan troglodytes
A2T6X9
766
85495
T627
H
G
S
A
L
A
N
T
S
P
C
D
H
I
Q
Rhesus Macaque
Macaca mulatta
XP_001108464
736
79383
S662
G
V
R
P
P
K
R
S
P
S
P
E
P
E
N
Dog
Lupus familis
XP_533636
651
70738
A578
P
S
A
S
S
S
M
A
G
A
R
K
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBL6
662
73002
S588
E
T
K
P
P
K
R
S
P
R
L
E
P
G
S
Rat
Rattus norvegicus
Q9JHS2
662
72869
S588
E
T
K
P
P
K
R
S
P
R
L
E
P
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510942
994
109832
P856
E
M
S
H
P
R
S
P
N
L
L
S
V
T
L
Chicken
Gallus gallus
Q9YIB9
811
90524
M707
N
A
Q
R
K
R
K
M
E
H
D
G
S
L
F
Frog
Xenopus laevis
Q9I8A9
805
90946
L669
S
R
P
G
T
P
N
L
P
V
P
L
N
K
R
Zebra Danio
Brachydanio rerio
Q98SJ5
745
82716
D643
R
L
S
S
P
L
P
D
R
L
S
K
G
K
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.8
87.7
86
N.A.
81.4
79.3
N.A.
29.6
36.5
33.9
27.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
42.1
89.1
88.9
N.A.
87
85.1
N.A.
42
51.2
47.9
42.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
0
N.A.
46.6
46.6
N.A.
6.6
0
13.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
20
N.A.
60
60
N.A.
20
20
26.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
10
0
10
0
10
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
10
% D
% Glu:
30
0
0
0
0
0
0
0
10
0
0
40
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
20
10
0
10
0
0
0
0
10
0
0
10
10
20
0
% G
% His:
10
0
0
10
0
0
0
0
0
10
0
0
20
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
20
0
10
40
10
0
0
0
0
20
0
20
0
% K
% Leu:
0
10
0
0
10
10
0
10
0
20
30
10
0
10
20
% L
% Met:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
20
0
10
0
0
0
10
0
20
% N
% Pro:
10
0
10
40
60
10
10
10
50
10
30
0
30
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Q
% Arg:
10
10
20
10
0
20
40
0
10
20
10
0
10
0
10
% R
% Ser:
10
10
30
20
10
10
10
40
10
20
10
10
10
0
20
% S
% Thr:
0
20
0
0
10
0
0
10
0
0
0
0
0
20
0
% T
% Val:
0
20
0
0
0
0
0
0
0
10
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _