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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIF3A All Species: 22.42
Human Site: T171 Identified Species: 54.81
UniProt: Q9Y2N7 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2N7 NP_071907.3 669 72433 T171 F S L R M K S T L T S R G R T
Chimpanzee Pan troglodytes A2T6X9 766 85495 K165 R S F F L R M K C V L A K R N
Rhesus Macaque Macaca mulatta XP_001108464 736 79383 T238 F S L R M K S T L T S R G R T
Dog Lupus familis XP_533636 651 70738 R160 L Q D A L T P R Q S L S K K K
Cat Felis silvestris
Mouse Mus musculus Q0VBL6 662 73002 T169 F S L R M K S T L T S R G R T
Rat Rattus norvegicus Q9JHS2 662 72869 T169 F S L R M K S T L T S R G R A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510942 994 109832 T360 F F L R M K C T L T S R G R T
Chicken Gallus gallus Q9YIB9 811 90524 T174 F F L R M K C T L T S R G R T
Frog Xenopus laevis Q9I8A9 805 90946 Y174 F L P S Y E M Y I N Q S W K N
Zebra Danio Brachydanio rerio Q98SJ5 745 82716 K165 R S F F L R M K C V L A K A N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.8 87.7 86 N.A. 81.4 79.3 N.A. 29.6 36.5 33.9 27.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 42.1 89.1 88.9 N.A. 87 85.1 N.A. 42 51.2 47.9 42.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 0 N.A. 100 93.3 N.A. 86.6 86.6 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 100 20 N.A. 100 93.3 N.A. 86.6 86.6 26.6 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 20 0 10 10 % A
% Cys: 0 0 0 0 0 0 20 0 20 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 70 20 20 20 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 60 0 20 0 0 0 0 30 20 10 % K
% Leu: 10 10 60 0 30 0 0 0 60 0 30 0 0 0 0 % L
% Met: 0 0 0 0 60 0 30 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 30 % N
% Pro: 0 0 10 0 0 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 20 0 0 60 0 20 0 10 0 0 0 60 0 70 0 % R
% Ser: 0 60 0 10 0 0 40 0 0 10 60 20 0 0 0 % S
% Thr: 0 0 0 0 0 10 0 60 0 60 0 0 0 0 50 % T
% Val: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _