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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RCL1
All Species:
41.21
Human Site:
T121
Identified Species:
69.74
UniProt:
Q9Y2P8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2P8
NP_005763.3
373
40843
T121
K
I
V
L
R
G
V
T
N
D
Q
V
D
P
S
Chimpanzee
Pan troglodytes
XP_520471
373
40721
T121
K
I
V
L
R
G
V
T
N
D
Q
V
D
P
S
Rhesus Macaque
Macaca mulatta
XP_001084388
373
40831
T121
K
I
V
L
R
G
V
T
N
D
Q
V
D
P
S
Dog
Lupus familis
XP_541299
477
51320
T225
R
I
V
L
R
G
V
T
N
D
Q
V
D
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJT0
373
40822
T121
K
I
V
L
R
G
V
T
N
D
Q
V
D
P
S
Rat
Rattus norvegicus
NP_001013170
215
23176
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505404
278
30048
K46
A
T
A
L
P
L
L
K
Q
F
G
I
D
G
E
Chicken
Gallus gallus
XP_424808
374
41022
T122
K
I
V
L
R
G
V
T
N
D
Q
V
D
P
S
Frog
Xenopus laevis
NP_001079592
372
40937
T121
K
I
T
L
R
G
V
T
N
D
Q
V
D
P
S
Zebra Danio
Brachydanio rerio
NP_001003865
367
40343
T114
K
A
V
L
K
G
I
T
N
H
P
T
D
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P56175
384
42072
T125
Q
C
T
L
R
G
V
T
N
S
K
D
S
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23400
379
41578
T119
V
I
K
L
K
G
V
T
N
A
P
G
E
I
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C578
375
40856
T119
S
I
R
L
K
G
I
T
N
D
P
R
D
A
S
Baker's Yeast
Sacchar. cerevisiae
Q08096
367
40152
T122
S
I
L
F
K
G
I
T
A
S
H
N
D
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
99.4
75.4
N.A.
97
55.2
N.A.
65.1
85.5
80.4
75.3
N.A.
53.1
N.A.
47.2
N.A.
Protein Similarity:
100
98.6
99.7
77.3
N.A.
99.7
57
N.A.
70.7
94.1
92.2
87.6
N.A.
70.3
N.A.
66.7
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
13.3
100
93.3
60
N.A.
53.3
N.A.
46.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
26.6
100
93.3
73.3
N.A.
66.6
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
45.6
37.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.9
60.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
0
0
0
8
8
0
0
0
15
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
58
0
8
79
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
86
0
0
0
0
8
8
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% H
% Ile:
0
72
0
0
0
0
22
0
0
0
0
8
0
8
0
% I
% Lys:
50
0
8
0
29
0
0
8
0
0
8
0
0
0
0
% K
% Leu:
0
0
8
86
0
8
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
79
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
22
0
0
65
0
% P
% Gln:
8
0
0
0
0
0
0
0
8
0
50
0
0
0
0
% Q
% Arg:
8
0
8
0
58
0
0
0
0
0
0
8
0
0
0
% R
% Ser:
15
0
0
0
0
0
0
0
0
15
0
0
8
0
79
% S
% Thr:
0
8
15
0
0
0
0
86
0
0
0
8
0
0
0
% T
% Val:
8
0
50
0
0
0
65
0
0
0
0
50
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _