KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A1
All Species:
19.39
Human Site:
S171
Identified Species:
35.56
UniProt:
Q9Y2Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Q0
NP_006086.1
1164
131369
S171
H
L
P
A
D
L
I
S
L
S
S
S
E
P
Q
Chimpanzee
Pan troglodytes
XP_001150768
1164
131363
S171
H
L
P
A
D
L
I
S
L
S
S
S
E
P
Q
Rhesus Macaque
Macaca mulatta
XP_001099138
1164
131392
S171
H
L
P
A
D
L
I
S
L
S
S
S
E
P
Q
Dog
Lupus familis
XP_849357
1158
131123
S171
H
L
P
A
D
L
I
S
L
S
S
S
E
P
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70704
1149
129748
N152
I
V
H
W
E
K
V
N
V
G
D
I
V
I
I
Rat
Rattus norvegicus
XP_223390
1134
128100
W148
G
A
W
E
I
V
H
W
E
K
V
A
V
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
Chicken
Gallus gallus
XP_420729
1223
137907
S230
H
L
P
A
D
L
I
S
L
S
S
S
E
P
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
T332
T
V
R
W
S
E
L
T
V
G
D
I
I
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
R153
V
Q
I
G
D
V
V
R
V
K
R
G
E
F
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
F172
F
F
P
A
D
I
L
F
M
S
S
T
N
S
D
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
I322
P
I
P
A
D
T
I
I
L
S
S
S
E
P
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.8
96.9
N.A.
95.8
94.5
N.A.
74.4
88.5
N.A.
53.8
N.A.
50.9
N.A.
N.A.
57.6
Protein Similarity:
100
100
100
98
N.A.
97.7
96.3
N.A.
76.9
92.4
N.A.
63.4
N.A.
65.4
N.A.
N.A.
74.8
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
0
100
N.A.
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
33.3
20
N.A.
0
100
N.A.
0
N.A.
26.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
39.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.6
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
33.3
66.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
54
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
62
0
0
0
0
0
16
0
0
0
8
% D
% Glu:
0
0
0
8
8
8
0
0
8
0
0
0
54
0
16
% E
% Phe:
8
8
0
0
0
0
0
8
0
0
0
0
0
8
8
% F
% Gly:
8
0
0
8
0
0
0
0
0
16
0
8
0
8
0
% G
% His:
39
0
8
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
8
0
8
8
47
8
0
0
0
16
8
8
8
% I
% Lys:
0
0
0
0
0
8
0
0
0
16
0
0
0
8
0
% K
% Leu:
0
39
0
0
0
39
16
0
47
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% N
% Pro:
8
0
54
0
0
0
0
0
0
0
0
0
0
47
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
39
% Q
% Arg:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
39
0
54
54
47
0
8
0
% S
% Thr:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% T
% Val:
8
16
0
0
0
16
16
0
24
0
8
0
16
0
8
% V
% Trp:
0
0
8
16
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _