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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A1
All Species:
22.73
Human Site:
T722
Identified Species:
41.67
UniProt:
Q9Y2Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Q0
NP_006086.1
1164
131369
T722
S
L
D
G
T
R
E
T
L
S
R
H
C
T
T
Chimpanzee
Pan troglodytes
XP_001150768
1164
131363
T722
S
L
D
G
T
R
E
T
L
S
R
H
C
T
T
Rhesus Macaque
Macaca mulatta
XP_001099138
1164
131392
T722
S
L
D
G
T
R
E
T
L
S
R
H
C
T
T
Dog
Lupus familis
XP_849357
1158
131123
L717
L
D
A
T
R
E
T
L
G
R
H
C
T
I
L
Cat
Felis silvestris
Mouse
Mus musculus
P70704
1149
129748
T707
S
L
D
G
T
R
E
T
L
S
R
H
C
T
T
Rat
Rattus norvegicus
XP_223390
1134
128100
N694
D
K
Q
E
T
A
I
N
I
G
H
S
C
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
R497
K
L
S
Q
H
C
T
R
L
G
D
A
L
R
K
Chicken
Gallus gallus
XP_420729
1223
137907
T781
S
L
D
G
T
R
E
T
L
S
H
H
C
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
S481
P
D
L
D
C
D
R
S
M
E
D
F
S
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
V883
S
L
D
A
T
R
E
V
I
H
R
H
Y
G
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
T709
S
H
D
E
I
R
E
T
L
Q
R
H
I
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
S768
V
K
R
E
L
K
K
S
L
E
E
A
Q
H
S
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
N872
T
R
D
D
T
E
R
N
L
L
E
K
I
N
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.8
96.9
N.A.
95.8
94.5
N.A.
74.4
88.5
N.A.
53.8
N.A.
50.9
N.A.
N.A.
57.6
Protein Similarity:
100
100
100
98
N.A.
97.7
96.3
N.A.
76.9
92.4
N.A.
63.4
N.A.
65.4
N.A.
N.A.
74.8
P-Site Identity:
100
100
100
0
N.A.
100
13.3
N.A.
13.3
86.6
N.A.
0
N.A.
53.3
N.A.
N.A.
60
P-Site Similarity:
100
100
100
0
N.A.
100
20
N.A.
13.3
93.3
N.A.
13.3
N.A.
60
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
39.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.6
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
0
8
0
0
0
0
0
16
0
0
16
% A
% Cys:
0
0
0
0
8
8
0
0
0
0
0
8
47
0
0
% C
% Asp:
8
16
62
16
0
8
0
0
0
0
16
0
0
0
0
% D
% Glu:
0
0
0
24
0
16
54
0
0
16
16
0
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
39
0
0
0
0
8
16
0
0
0
8
0
% G
% His:
0
8
0
0
8
0
0
0
0
8
24
54
0
16
0
% H
% Ile:
0
0
0
0
8
0
8
0
16
0
0
0
16
8
0
% I
% Lys:
8
16
0
0
0
8
8
0
0
0
0
8
0
0
8
% K
% Leu:
8
54
8
0
8
0
0
8
70
8
0
0
8
0
24
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
8
0
0
0
0
0
8
0
0
8
0
0
% Q
% Arg:
0
8
8
0
8
54
16
8
0
8
47
0
0
16
0
% R
% Ser:
54
0
8
0
0
0
0
16
0
39
0
8
8
8
8
% S
% Thr:
8
0
0
8
62
0
16
47
0
0
0
0
8
39
39
% T
% Val:
8
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _