KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8A1
All Species:
21.21
Human Site:
Y382
Identified Species:
38.89
UniProt:
Q9Y2Q0
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2Q0
NP_006086.1
1164
131369
Y382
N
W
D
L
D
M
H
Y
E
P
T
D
T
A
A
Chimpanzee
Pan troglodytes
XP_001150768
1164
131363
Y382
N
W
D
L
D
M
H
Y
E
P
T
D
T
A
A
Rhesus Macaque
Macaca mulatta
XP_001099138
1164
131392
Y382
N
W
D
L
D
M
H
Y
E
P
T
D
T
A
A
Dog
Lupus familis
XP_849357
1158
131123
Y382
N
W
D
L
D
M
H
Y
E
P
T
D
T
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P70704
1149
129748
K367
L
V
T
L
E
V
V
K
F
T
Q
A
Y
F
I
Rat
Rattus norvegicus
XP_223390
1134
128100
I357
L
F
N
N
L
I
P
I
S
L
L
V
T
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518853
932
104820
V162
L
N
E
E
L
G
Q
V
K
Y
I
F
S
D
K
Chicken
Gallus gallus
XP_420729
1223
137907
Y441
N
W
D
I
D
M
H
Y
E
P
T
D
T
A
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666697
916
102033
I146
T
L
V
P
L
I
F
I
L
T
V
A
G
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137649
1324
149578
V541
L
I
P
I
S
L
Q
V
T
L
E
L
V
R
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200260
1167
132097
A368
E
L
V
K
F
G
Q
A
L
F
I
N
F
D
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
H386
N
R
D
L
N
M
Y
H
A
E
T
N
T
P
A
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
Y533
G
S
D
L
D
L
Y
Y
E
K
T
D
T
P
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.8
96.9
N.A.
95.8
94.5
N.A.
74.4
88.5
N.A.
53.8
N.A.
50.9
N.A.
N.A.
57.6
Protein Similarity:
100
100
100
98
N.A.
97.7
96.3
N.A.
76.9
92.4
N.A.
63.4
N.A.
65.4
N.A.
N.A.
74.8
P-Site Identity:
100
100
100
100
N.A.
6.6
6.6
N.A.
0
93.3
N.A.
0
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
20
26.6
N.A.
20
100
N.A.
6.6
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.2
39.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.6
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
8
0
0
16
0
39
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
54
0
47
0
0
0
0
0
0
47
0
16
0
% D
% Glu:
8
0
8
8
8
0
0
0
47
8
8
0
0
0
8
% E
% Phe:
0
8
0
0
8
0
8
0
8
8
0
8
8
8
8
% F
% Gly:
8
0
0
0
0
16
0
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
39
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
16
0
16
0
16
0
0
16
0
0
8
8
% I
% Lys:
0
0
0
8
0
0
0
8
8
8
0
0
0
0
16
% K
% Leu:
31
16
0
54
24
16
0
0
16
16
8
8
0
8
8
% L
% Met:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% M
% Asn:
47
8
8
8
8
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
8
8
0
0
8
0
0
39
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
8
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
8
0
0
8
0
0
0
8
0
0
0
8
0
0
% S
% Thr:
8
0
8
0
0
0
0
0
8
16
54
0
62
0
8
% T
% Val:
0
8
16
0
0
8
8
16
0
0
8
8
8
0
0
% V
% Trp:
0
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
16
47
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _