KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPN22
All Species:
13.94
Human Site:
S668
Identified Species:
30.67
UniProt:
Q9Y2R2
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R2
NP_057051.3
807
91705
S668
E
P
K
K
F
D
D
S
V
I
L
R
P
S
K
Chimpanzee
Pan troglodytes
XP_513663
807
91678
S668
E
P
K
K
F
D
D
S
V
R
L
R
P
S
K
Rhesus Macaque
Macaca mulatta
XP_001110241
807
91482
S668
E
P
K
K
F
D
D
S
V
R
L
R
P
S
K
Dog
Lupus familis
XP_540240
893
101055
V754
L
N
T
S
D
D
S
V
R
L
R
P
T
K
S
Cat
Felis silvestris
Mouse
Mus musculus
P29352
802
89696
D663
T
S
E
M
K
S
H
D
S
V
G
F
T
P
S
Rat
Rattus norvegicus
NP_001099930
804
89584
D665
T
S
E
S
Q
S
H
D
L
V
A
F
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506530
800
89754
S661
E
S
K
A
S
D
D
S
V
R
M
R
P
S
K
Chicken
Gallus gallus
XP_001235234
775
85980
N637
V
P
P
S
V
T
S
N
D
S
V
R
L
R
P
Frog
Xenopus laevis
NP_001084841
660
74123
S522
L
E
K
G
L
S
V
S
S
G
M
C
K
N
V
Zebra Danio
Brachydanio rerio
NP_956963
570
64484
Q432
E
R
L
A
V
E
I
Q
K
V
A
L
Q
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796904
967
106580
S701
S
R
S
S
R
K
N
S
D
E
Y
A
Y
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
95.5
71.1
N.A.
71.1
69.2
N.A.
57.1
50.8
36.3
34.3
N.A.
N.A.
N.A.
N.A.
28.2
Protein Similarity:
100
99.8
97
77.9
N.A.
80.4
79.3
N.A.
68
64
50.9
49.9
N.A.
N.A.
N.A.
N.A.
44.7
P-Site Identity:
100
93.3
93.3
6.6
N.A.
0
6.6
N.A.
66.6
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
93.3
13.3
N.A.
13.3
26.6
N.A.
73.3
26.6
26.6
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
0
0
0
19
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
0
10
46
37
19
19
0
0
0
0
0
0
% D
% Glu:
46
10
19
0
0
10
0
0
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
0
28
0
0
0
0
0
0
19
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
0
10
10
0
0
0
10
% G
% His:
0
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
46
28
10
10
0
0
10
0
0
0
10
10
37
% K
% Leu:
19
0
10
0
10
0
0
0
10
10
28
10
10
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
19
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
10
0
0
0
0
0
10
0
% N
% Pro:
0
37
10
0
0
0
0
0
0
0
0
10
37
10
10
% P
% Gln:
0
0
0
0
10
0
0
10
0
0
0
0
10
0
10
% Q
% Arg:
0
19
0
0
10
0
0
0
10
28
10
46
0
10
0
% R
% Ser:
10
28
10
37
10
28
19
55
19
10
0
0
0
46
28
% S
% Thr:
19
0
10
0
0
10
0
0
0
0
0
0
28
0
0
% T
% Val:
10
0
0
0
19
0
10
10
37
28
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _