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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX52
All Species:
10.91
Human Site:
S111
Identified Species:
18.46
UniProt:
Q9Y2R4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R4
NP_008941.2
599
67466
S111
A
T
I
Q
W
M
S
S
V
E
A
K
I
E
D
Chimpanzee
Pan troglodytes
XP_511433
599
67493
S111
A
T
I
Q
W
M
S
S
V
E
A
K
I
E
D
Rhesus Macaque
Macaca mulatta
XP_001112113
599
67671
S111
A
T
I
Q
W
I
S
S
V
E
A
K
I
E
D
Dog
Lupus familis
XP_548903
598
67829
V111
T
I
Q
W
T
S
S
V
E
A
K
I
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K301
598
67424
S111
D
G
G
I
Q
W
T
S
S
V
E
A
K
L
Q
Rat
Rattus norvegicus
Q99PT0
598
67221
S111
D
G
T
I
Q
W
T
S
S
V
E
A
K
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025896
603
67755
K111
W
M
S
S
L
E
A
K
V
K
D
T
K
D
N
Frog
Xenopus laevis
NP_001086456
614
69109
S111
D
V
S
A
G
D
E
S
I
L
W
M
S
S
L
Zebra Danio
Brachydanio rerio
NP_001037780
606
68239
W111
R
E
G
E
G
I
Q
W
M
S
L
Q
N
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649009
594
67525
Q100
E
A
N
E
T
R
K
Q
Y
G
I
R
V
L
G
Honey Bee
Apis mellifera
XP_001120427
494
56794
L46
I
K
E
K
Q
L
K
L
A
Q
E
K
I
N
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TG1
541
60898
E93
A
R
A
K
G
K
A
E
E
Q
I
T
K
N
E
Baker's Yeast
Sacchar. cerevisiae
P45818
564
63634
L100
N
T
V
E
A
S
A
L
R
K
S
Y
K
G
N
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
K155
V
R
A
R
D
Q
P
K
P
G
N
T
T
A
K
Conservation
Percent
Protein Identity:
100
99.5
97.8
93.9
N.A.
88.9
88.1
N.A.
N.A.
71.9
69
62.3
N.A.
46.4
49.5
N.A.
N.A.
Protein Similarity:
100
100
98.8
96.8
N.A.
93.3
92.6
N.A.
N.A.
82.2
82.2
79.5
N.A.
65.2
63.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
6.6
0
N.A.
0
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
N.A.
33.3
13.3
33.3
N.A.
20
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.9
40
20.6
Protein Similarity:
N.A.
N.A.
N.A.
57.7
59.6
32.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
46.6
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
15
8
8
0
22
0
8
8
22
15
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
0
0
0
8
8
0
0
0
0
8
0
0
15
22
% D
% Glu:
8
8
8
22
0
8
8
8
15
22
22
0
8
22
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
15
15
0
22
0
0
0
0
15
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
8
22
15
0
15
0
0
8
0
15
8
29
0
0
% I
% Lys:
0
8
0
15
0
8
15
15
0
15
8
29
36
8
15
% K
% Leu:
0
0
0
0
8
8
0
15
0
8
8
0
0
22
8
% L
% Met:
0
8
0
0
0
15
0
0
8
0
0
8
0
0
0
% M
% Asn:
8
0
8
0
0
0
0
0
0
0
8
0
8
15
15
% N
% Pro:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
22
22
8
8
8
0
15
0
8
0
0
22
% Q
% Arg:
8
15
0
8
0
8
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
15
8
0
15
29
43
15
8
8
0
8
8
0
% S
% Thr:
8
29
8
0
15
0
15
0
0
0
0
22
8
0
8
% T
% Val:
8
8
8
0
0
0
0
8
29
15
0
0
8
0
0
% V
% Trp:
8
0
0
8
22
15
0
8
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _