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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX52
All Species:
12.42
Human Site:
S125
Identified Species:
21.03
UniProt:
Q9Y2R4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R4
NP_008941.2
599
67466
S125
D
K
K
V
Q
R
E
S
K
L
T
S
G
K
L
Chimpanzee
Pan troglodytes
XP_511433
599
67493
S125
D
K
K
V
Q
R
E
S
K
L
T
S
G
K
L
Rhesus Macaque
Macaca mulatta
XP_001112113
599
67671
S125
D
K
K
V
P
R
E
S
K
L
T
S
G
K
L
Dog
Lupus familis
XP_548903
598
67829
K125
K
K
I
K
R
E
N
K
L
T
S
G
K
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K301
598
67424
E125
Q
E
E
K
V
S
G
E
K
K
L
T
S
G
K
Rat
Rattus norvegicus
Q99PT0
598
67221
E125
Q
D
K
K
A
N
G
E
K
K
L
T
S
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025896
603
67755
K125
N
K
K
P
T
A
E
K
L
E
R
L
R
R
E
Frog
Xenopus laevis
NP_001086456
614
69109
G125
L
E
A
K
L
Q
D
G
K
G
K
S
K
K
K
Zebra Danio
Brachydanio rerio
NP_001037780
606
68239
S125
T
K
E
A
K
Q
E
S
K
D
K
P
S
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649009
594
67525
V114
G
K
N
V
P
P
P
V
D
S
F
G
T
L
T
Honey Bee
Apis mellifera
XP_001120427
494
56794
I60
Q
H
R
N
Q
Y
H
I
S
V
T
G
N
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TG1
541
60898
K107
E
I
V
E
N
P
K
K
E
L
N
R
Q
M
E
Baker's Yeast
Sacchar. cerevisiae
P45818
564
63634
P114
N
V
S
G
I
D
I
P
L
P
I
G
S
F
E
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
S169
K
E
N
E
P
A
K
S
T
P
T
Q
P
Q
T
Conservation
Percent
Protein Identity:
100
99.5
97.8
93.9
N.A.
88.9
88.1
N.A.
N.A.
71.9
69
62.3
N.A.
46.4
49.5
N.A.
N.A.
Protein Similarity:
100
100
98.8
96.8
N.A.
93.3
92.6
N.A.
N.A.
82.2
82.2
79.5
N.A.
65.2
63.4
N.A.
N.A.
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
13.3
N.A.
N.A.
20
20
26.6
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
20
N.A.
26.6
26.6
N.A.
N.A.
33.3
40
46.6
N.A.
13.3
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.9
40
20.6
Protein Similarity:
N.A.
N.A.
N.A.
57.7
59.6
32.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
8
15
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
22
8
0
0
0
8
8
0
8
8
0
0
0
0
0
% D
% Glu:
8
22
15
15
0
8
36
15
8
8
0
0
0
8
29
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% F
% Gly:
8
0
0
8
0
0
15
8
0
8
0
29
22
8
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
8
8
0
0
8
0
0
0
8
% I
% Lys:
15
50
36
29
8
0
15
22
50
15
15
0
15
29
29
% K
% Leu:
8
0
0
0
8
0
0
0
22
29
15
8
0
22
22
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
15
0
15
8
8
8
8
0
0
0
8
0
8
0
0
% N
% Pro:
0
0
0
8
22
15
8
8
0
15
0
8
8
0
0
% P
% Gln:
22
0
0
0
22
15
0
0
0
0
0
8
8
8
0
% Q
% Arg:
0
0
8
0
8
22
0
0
0
0
8
8
8
15
0
% R
% Ser:
0
0
8
0
0
8
0
36
8
8
8
29
29
0
0
% S
% Thr:
8
0
0
0
8
0
0
0
8
8
36
15
8
0
15
% T
% Val:
0
8
8
29
8
0
0
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _