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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX52 All Species: 26.67
Human Site: S22 Identified Species: 45.13
UniProt: Q9Y2R4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2R4 NP_008941.2 599 67466 S22 K F D T R R F S A D A A R F Q
Chimpanzee Pan troglodytes XP_511433 599 67493 S22 K F D T R R F S A D A A R F K
Rhesus Macaque Macaca mulatta XP_001112113 599 67671 S22 K F D T R R F S A D A A R F Q
Dog Lupus familis XP_548903 598 67829 S22 K F D V R H F S A D A A R F Q
Cat Felis silvestris
Mouse Mus musculus Q8K301 598 67424 S22 K F D V K R F S A D A T R F Q
Rat Rattus norvegicus Q99PT0 598 67221 S22 K F D V K R F S A D A T R F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025896 603 67755 G22 R F D V R R F G L D A R R F G
Frog Xenopus laevis NP_001086456 614 69109 S22 R F D L K R F S G D A E K F K
Zebra Danio Brachydanio rerio NP_001037780 606 68239 A22 K F D L K R F A K D A E R F K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649009 594 67525 T11 H D I F K L I T A G V R F T K
Honey Bee Apis mellifera XP_001120427 494 56794
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84TG1 541 60898
Baker's Yeast Sacchar. cerevisiae P45818 564 63634 A11 F R V L T R G A S V K K E S G
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 S66 R D G R D R D S Y R R R D R S
Conservation
Percent
Protein Identity: 100 99.5 97.8 93.9 N.A. 88.9 88.1 N.A. N.A. 71.9 69 62.3 N.A. 46.4 49.5 N.A. N.A.
Protein Similarity: 100 100 98.8 96.8 N.A. 93.3 92.6 N.A. N.A. 82.2 82.2 79.5 N.A. 65.2 63.4 N.A. N.A.
P-Site Identity: 100 93.3 100 86.6 N.A. 80 80 N.A. N.A. 60 53.3 60 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 86.6 N.A. N.A. 66.6 80 80 N.A. 26.6 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.9 40 20.6
Protein Similarity: N.A. N.A. N.A. 57.7 59.6 32.5
P-Site Identity: N.A. N.A. N.A. 0 6.6 13.3
P-Site Similarity: N.A. N.A. N.A. 0 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 15 50 0 65 29 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 15 65 0 8 0 8 0 0 65 0 0 8 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 15 8 0 0 % E
% Phe: 8 65 0 8 0 0 65 0 0 0 0 0 8 65 0 % F
% Gly: 0 0 8 0 0 0 8 8 8 8 0 0 0 0 15 % G
% His: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % I
% Lys: 50 0 0 0 36 0 0 0 8 0 8 8 8 0 29 % K
% Leu: 0 0 0 22 0 8 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 36 % Q
% Arg: 22 8 0 8 36 72 0 0 0 8 8 22 58 8 0 % R
% Ser: 0 0 0 0 0 0 0 58 8 0 0 0 0 8 8 % S
% Thr: 0 0 0 22 8 0 0 8 0 0 0 15 0 8 0 % T
% Val: 0 0 8 29 0 0 0 0 0 8 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _