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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX52
All Species:
34.55
Human Site:
S248
Identified Species:
58.46
UniProt:
Q9Y2R4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R4
NP_008941.2
599
67466
S248
S
P
T
R
E
L
A
S
Q
I
H
R
E
L
I
Chimpanzee
Pan troglodytes
XP_511433
599
67493
S248
S
P
T
R
E
L
A
S
Q
I
H
R
E
L
I
Rhesus Macaque
Macaca mulatta
XP_001112113
599
67671
S248
S
P
T
R
E
L
A
S
Q
I
H
R
E
L
I
Dog
Lupus familis
XP_548903
598
67829
N247
S
P
T
R
E
L
A
N
Q
I
H
R
E
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8K301
598
67424
S249
S
P
T
R
E
L
A
S
Q
I
H
R
E
L
I
Rat
Rattus norvegicus
Q99PT0
598
67221
S249
S
P
T
R
E
L
A
S
Q
I
H
R
E
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025896
603
67755
S242
S
P
T
R
E
L
A
S
Q
T
H
R
E
L
V
Frog
Xenopus laevis
NP_001086456
614
69109
S254
S
P
T
R
E
L
A
S
Q
T
H
R
E
L
V
Zebra Danio
Brachydanio rerio
NP_001037780
606
68239
T250
S
P
T
R
E
L
A
T
Q
T
H
R
E
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649009
594
67525
L217
E
L
T
R
E
T
G
L
R
T
H
F
I
S
K
Honey Bee
Apis mellifera
XP_001120427
494
56794
R163
E
L
A
K
Q
T
Y
R
E
C
L
R
L
S
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TG1
541
60898
G210
L
K
R
P
S
T
D
G
I
R
A
V
I
L
S
Baker's Yeast
Sacchar. cerevisiae
P45818
564
63634
L221
K
L
S
Y
K
I
F
L
E
K
K
R
P
L
Q
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
T648
T
P
T
R
E
L
C
T
Q
I
Y
S
D
L
Q
Conservation
Percent
Protein Identity:
100
99.5
97.8
93.9
N.A.
88.9
88.1
N.A.
N.A.
71.9
69
62.3
N.A.
46.4
49.5
N.A.
N.A.
Protein Similarity:
100
100
98.8
96.8
N.A.
93.3
92.6
N.A.
N.A.
82.2
82.2
79.5
N.A.
65.2
63.4
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
N.A.
86.6
86.6
80
N.A.
26.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
33.3
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.9
40
20.6
Protein Similarity:
N.A.
N.A.
N.A.
57.7
59.6
32.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
65
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% D
% Glu:
15
0
0
0
79
0
0
0
15
0
0
0
65
0
8
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
72
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
50
0
0
15
0
36
% I
% Lys:
8
8
0
8
8
0
0
0
0
8
8
0
0
0
8
% K
% Leu:
8
22
0
0
0
72
0
15
0
0
8
0
8
86
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
72
0
8
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
72
0
0
0
0
0
15
% Q
% Arg:
0
0
8
79
0
0
0
8
8
8
0
79
0
0
0
% R
% Ser:
65
0
8
0
8
0
0
50
0
0
0
8
0
15
8
% S
% Thr:
8
0
79
0
0
22
0
15
0
29
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
8
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _