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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX52 All Species: 10.91
Human Site: S86 Identified Species: 18.46
UniProt: Q9Y2R4 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.46
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2R4 NP_008941.2 599 67466 S86 T E R K R E Q S K K K R K T M
Chimpanzee Pan troglodytes XP_511433 599 67493 S86 T E R K R E Q S K K K R K T M
Rhesus Macaque Macaca mulatta XP_001112113 599 67671 S86 T E R K K E Q S K K K R K M M
Dog Lupus familis XP_548903 598 67829 N86 T E R K R E Q N K K K R K M I
Cat Felis silvestris
Mouse Mus musculus Q8K301 598 67424 K86 L E R S K E P K K K K R K K M
Rat Rattus norvegicus Q99PT0 598 67221 K86 L E R S K E P K K K K R K K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001025896 603 67755 K86 S G K R K R K K R Q E T V S V
Frog Xenopus laevis NP_001086456 614 69109 K86 N K A S K R K K D L G R G V K
Zebra Danio Brachydanio rerio NP_001037780 606 68239 R86 T E S L K A A R K K K K G A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649009 594 67525 K75 Q P K R K K P K K E K T L S P
Honey Bee Apis mellifera XP_001120427 494 56794 F21 V K F D K K R F Q I D A E R F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q84TG1 541 60898 S68 S K K R K R R S S N S V P V E
Baker's Yeast Sacchar. cerevisiae P45818 564 63634 N75 T T E N D S P N K E E K S G N
Red Bread Mold Neurospora crassa Q7SH33 1194 131283 A130 R D D S R D R A R V R R E G T
Conservation
Percent
Protein Identity: 100 99.5 97.8 93.9 N.A. 88.9 88.1 N.A. N.A. 71.9 69 62.3 N.A. 46.4 49.5 N.A. N.A.
Protein Similarity: 100 100 98.8 96.8 N.A. 93.3 92.6 N.A. N.A. 82.2 82.2 79.5 N.A. 65.2 63.4 N.A. N.A.
P-Site Identity: 100 100 86.6 80 N.A. 60 60 N.A. N.A. 0 6.6 33.3 N.A. 13.3 0 N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 66.6 66.6 N.A. N.A. 66.6 26.6 46.6 N.A. 53.3 40 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 39.9 40 20.6
Protein Similarity: N.A. N.A. N.A. 57.7 59.6 32.5
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 46.6 40 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 8 8 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 8 8 8 8 0 0 8 0 8 0 0 0 0 % D
% Glu: 0 50 8 0 0 43 0 0 0 15 15 0 15 0 8 % E
% Phe: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 8 % F
% Gly: 0 8 0 0 0 0 0 0 0 0 8 0 15 15 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 8 % I
% Lys: 0 22 22 29 65 15 15 36 65 50 58 15 43 15 15 % K
% Leu: 15 0 0 8 0 0 0 0 0 8 0 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 36 % M
% Asn: 8 0 0 8 0 0 0 15 0 8 0 0 0 0 8 % N
% Pro: 0 8 0 0 0 0 29 0 0 0 0 0 8 0 8 % P
% Gln: 8 0 0 0 0 0 29 0 8 8 0 0 0 0 0 % Q
% Arg: 8 0 43 22 29 22 22 8 15 0 8 58 0 8 0 % R
% Ser: 15 0 8 29 0 8 0 29 8 0 8 0 8 15 0 % S
% Thr: 43 8 0 0 0 0 0 0 0 0 0 15 0 15 8 % T
% Val: 8 0 0 0 0 0 0 0 0 8 0 8 8 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _