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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX52
All Species:
10
Human Site:
T105
Identified Species:
16.92
UniProt:
Q9Y2R4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R4
NP_008941.2
599
67466
T105
A
S
Q
E
E
G
A
T
I
Q
W
M
S
S
V
Chimpanzee
Pan troglodytes
XP_511433
599
67493
T105
A
S
Q
E
E
G
A
T
I
Q
W
M
S
S
V
Rhesus Macaque
Macaca mulatta
XP_001112113
599
67671
T105
T
S
Q
E
E
G
A
T
I
Q
W
I
S
S
V
Dog
Lupus familis
XP_548903
598
67829
I105
S
Q
E
E
G
S
T
I
Q
W
T
S
S
V
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K301
598
67424
G105
P
A
Q
E
D
L
D
G
G
I
Q
W
T
S
S
Rat
Rattus norvegicus
Q99PT0
598
67221
G105
P
A
Q
E
D
L
D
G
T
I
Q
W
T
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025896
603
67755
M105
E
S
D
G
I
M
W
M
S
S
L
E
A
K
V
Frog
Xenopus laevis
NP_001086456
614
69109
V105
Q
E
S
D
A
G
D
V
S
A
G
D
E
S
I
Zebra Danio
Brachydanio rerio
NP_001037780
606
68239
E105
D
A
E
P
E
T
R
E
G
E
G
I
Q
W
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649009
594
67525
A94
I
Q
K
A
A
E
E
A
N
E
T
R
K
Q
Y
Honey Bee
Apis mellifera
XP_001120427
494
56794
K40
K
Q
S
E
N
I
I
K
E
K
Q
L
K
L
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TG1
541
60898
R87
F
K
S
S
K
K
A
R
A
K
G
K
A
E
E
Baker's Yeast
Sacchar. cerevisiae
P45818
564
63634
T94
I
K
P
V
I
T
N
T
V
E
A
S
A
L
R
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
R149
S
H
R
R
D
D
V
R
A
R
D
Q
P
K
P
Conservation
Percent
Protein Identity:
100
99.5
97.8
93.9
N.A.
88.9
88.1
N.A.
N.A.
71.9
69
62.3
N.A.
46.4
49.5
N.A.
N.A.
Protein Similarity:
100
100
98.8
96.8
N.A.
93.3
92.6
N.A.
N.A.
82.2
82.2
79.5
N.A.
65.2
63.4
N.A.
N.A.
P-Site Identity:
100
100
86.6
13.3
N.A.
20
20
N.A.
N.A.
13.3
13.3
6.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
40
40
N.A.
N.A.
20
26.6
40
N.A.
13.3
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.9
40
20.6
Protein Similarity:
N.A.
N.A.
N.A.
57.7
59.6
32.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
26.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
22
0
8
15
0
29
8
15
8
8
0
22
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
8
22
8
22
0
0
0
8
8
0
0
0
% D
% Glu:
8
8
15
50
29
8
8
8
8
22
0
8
8
8
15
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
29
0
15
15
0
22
0
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
15
8
8
8
22
15
0
15
0
0
8
% I
% Lys:
8
15
8
0
8
8
0
8
0
15
0
8
15
15
0
% K
% Leu:
0
0
0
0
0
15
0
0
0
0
8
8
0
15
0
% L
% Met:
0
0
0
0
0
8
0
8
0
0
0
15
0
0
8
% M
% Asn:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% N
% Pro:
15
0
8
8
0
0
0
0
0
0
0
0
8
0
8
% P
% Gln:
8
22
36
0
0
0
0
0
8
22
22
8
8
8
0
% Q
% Arg:
0
0
8
8
0
0
8
15
0
8
0
8
0
0
8
% R
% Ser:
15
29
22
8
0
8
0
0
15
8
0
15
29
43
15
% S
% Thr:
8
0
0
0
0
15
8
29
8
0
15
0
15
0
0
% T
% Val:
0
0
0
8
0
0
8
8
8
0
0
0
0
8
29
% V
% Trp:
0
0
0
0
0
0
8
0
0
8
22
15
0
8
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _