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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX52
All Species:
33.33
Human Site:
T569
Identified Species:
56.41
UniProt:
Q9Y2R4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R4
NP_008941.2
599
67466
T569
E
R
E
S
I
S
T
T
P
K
C
F
L
E
K
Chimpanzee
Pan troglodytes
XP_511433
599
67493
T569
E
R
E
S
I
S
T
T
P
K
C
F
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001112113
599
67671
T569
E
R
E
S
I
S
T
T
P
K
C
F
L
E
K
Dog
Lupus familis
XP_548903
598
67829
T568
E
R
E
S
I
S
T
T
P
K
Y
F
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K301
598
67424
T570
E
R
E
S
I
C
T
T
P
K
Y
F
L
E
Q
Rat
Rattus norvegicus
Q99PT0
598
67221
T570
E
R
E
S
I
S
T
T
P
K
Y
F
L
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025896
603
67755
T563
T
R
E
A
I
C
T
T
P
Q
C
F
L
K
K
Frog
Xenopus laevis
NP_001086456
614
69109
T575
K
R
D
Q
I
R
T
T
P
K
Y
I
L
E
K
Zebra Danio
Brachydanio rerio
NP_001037780
606
68239
T571
R
R
A
A
I
R
T
T
P
R
M
L
F
D
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649009
594
67525
K523
D
R
E
D
I
S
T
K
I
R
P
E
T
K
G
Honey Bee
Apis mellifera
XP_001120427
494
56794
K466
H
S
K
K
E
K
R
K
L
E
H
K
A
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TG1
541
60898
L513
V
P
S
W
I
M
S
L
K
K
K
K
W
R
K
Baker's Yeast
Sacchar. cerevisiae
P45818
564
63634
T529
H
K
E
R
K
Q
I
T
T
V
P
K
M
D
K
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
L968
S
G
F
G
G
K
G
L
E
K
L
D
K
D
R
Conservation
Percent
Protein Identity:
100
99.5
97.8
93.9
N.A.
88.9
88.1
N.A.
N.A.
71.9
69
62.3
N.A.
46.4
49.5
N.A.
N.A.
Protein Similarity:
100
100
98.8
96.8
N.A.
93.3
92.6
N.A.
N.A.
82.2
82.2
79.5
N.A.
65.2
63.4
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
86.6
N.A.
N.A.
66.6
60
33.3
N.A.
33.3
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
N.A.
86.6
73.3
60
N.A.
53.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.9
40
20.6
Protein Similarity:
N.A.
N.A.
N.A.
57.7
59.6
32.5
P-Site Identity:
N.A.
N.A.
N.A.
20
20
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
15
0
0
0
0
29
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
0
0
0
0
0
8
0
22
0
% D
% Glu:
43
0
65
0
8
0
0
0
8
8
0
8
0
50
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
50
8
0
0
% F
% Gly:
0
8
0
8
8
0
8
0
0
0
0
0
0
0
8
% G
% His:
15
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
79
0
8
0
8
0
0
8
0
0
0
% I
% Lys:
8
8
8
8
8
15
0
15
8
65
8
22
8
15
58
% K
% Leu:
0
0
0
0
0
0
0
15
8
0
8
8
58
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
65
0
15
0
0
8
0
% P
% Gln:
0
0
0
8
0
8
0
0
0
8
0
0
0
0
15
% Q
% Arg:
8
72
0
8
0
15
8
0
0
15
0
0
0
8
15
% R
% Ser:
8
8
8
43
0
43
8
0
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
72
72
8
0
0
0
8
0
8
% T
% Val:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
29
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _