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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX52
All Species:
33.94
Human Site:
Y170
Identified Species:
57.44
UniProt:
Q9Y2R4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2R4
NP_008941.2
599
67466
Y170
F
Q
Q
L
D
Q
E
Y
K
I
N
S
R
L
L
Chimpanzee
Pan troglodytes
XP_511433
599
67493
Y170
F
Q
Q
L
D
Q
E
Y
K
I
N
S
R
L
L
Rhesus Macaque
Macaca mulatta
XP_001112113
599
67671
Y170
F
Q
Q
L
D
Q
E
Y
K
I
N
S
R
L
L
Dog
Lupus familis
XP_548903
598
67829
Y169
F
Q
Q
L
D
Q
E
Y
K
I
N
S
R
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K301
598
67424
Y171
F
Q
Q
L
D
Q
E
Y
K
I
N
S
R
L
L
Rat
Rattus norvegicus
Q99PT0
598
67221
Y171
F
Q
Q
L
D
Q
E
Y
K
I
S
P
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001025896
603
67755
Y164
F
D
Q
L
Q
K
E
Y
K
V
H
P
K
V
I
Frog
Xenopus laevis
NP_001086456
614
69109
Y176
F
Q
Q
L
E
Q
E
Y
K
I
L
S
K
I
M
Zebra Danio
Brachydanio rerio
NP_001037780
606
68239
Y172
F
E
E
L
Q
K
E
Y
D
L
D
P
R
I
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649009
594
67525
A149
P
T
P
I
Q
M
Q
A
L
P
V
L
L
Q
R
Honey Bee
Apis mellifera
XP_001120427
494
56794
G95
I
N
N
V
I
N
C
G
Y
Q
Y
P
T
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84TG1
541
60898
L142
P
L
K
S
F
A
E
L
S
S
R
Y
G
C
E
Baker's Yeast
Sacchar. cerevisiae
P45818
564
63634
C152
P
T
P
I
Q
C
E
C
I
P
V
A
L
N
N
Red Bread Mold
Neurospora crassa
Q7SH33
1194
131283
C566
P
V
Q
K
W
S
Q
C
G
L
T
R
P
I
L
Conservation
Percent
Protein Identity:
100
99.5
97.8
93.9
N.A.
88.9
88.1
N.A.
N.A.
71.9
69
62.3
N.A.
46.4
49.5
N.A.
N.A.
Protein Similarity:
100
100
98.8
96.8
N.A.
93.3
92.6
N.A.
N.A.
82.2
82.2
79.5
N.A.
65.2
63.4
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
86.6
N.A.
N.A.
40
66.6
33.3
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
80
93.3
80
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.9
40
20.6
Protein Similarity:
N.A.
N.A.
N.A.
57.7
59.6
32.5
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
8
8
15
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
43
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
8
8
0
8
0
79
0
0
0
0
0
0
0
8
% E
% Phe:
65
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
8
0
0
15
8
0
0
0
8
50
0
0
0
22
22
% I
% Lys:
0
0
8
8
0
15
0
0
58
0
0
0
15
0
0
% K
% Leu:
0
8
0
65
0
0
0
8
8
15
8
8
15
43
50
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
8
8
0
0
8
0
0
0
0
36
0
0
8
8
% N
% Pro:
29
0
15
0
0
0
0
0
0
15
0
29
8
8
0
% P
% Gln:
0
50
65
0
29
50
15
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
8
50
0
8
% R
% Ser:
0
0
0
8
0
8
0
0
8
8
8
43
0
0
0
% S
% Thr:
0
15
0
0
0
0
0
0
0
0
8
0
8
0
0
% T
% Val:
0
8
0
8
0
0
0
0
0
8
15
0
0
8
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _