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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1D
All Species:
13.33
Human Site:
S76
Identified Species:
26.67
UniProt:
Q9Y2S0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2S0
NP_057056.1
133
15237
S76
G
Y
T
T
T
H
P
S
E
S
K
I
N
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110871
133
15192
S76
G
Y
T
T
T
H
P
S
E
S
K
I
N
L
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97304
133
15054
S76
G
Y
T
T
T
H
P
S
E
S
K
I
N
L
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514864
149
16940
G73
F
R
I
Q
T
R
G
G
L
P
A
V
E
P
F
Chicken
Gallus gallus
XP_426271
114
12998
R71
I
N
F
R
I
Q
T
R
G
S
L
P
A
V
E
Frog
Xenopus laevis
Q5XK67
114
13106
R71
I
N
F
R
I
Q
T
R
N
G
I
P
A
V
E
Zebra Danio
Brachydanio rerio
Q6DRI4
112
12737
T69
K
I
N
F
R
I
Q
T
R
D
G
V
P
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIZ0
105
11850
I62
E
Q
K
L
H
F
R
I
Q
S
R
R
D
R
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34476
144
16576
L97
G
Y
N
V
P
H
P
L
E
D
K
I
L
F
R
Sea Urchin
Strong. purpuratus
XP_794921
117
13094
R73
T
E
N
R
I
N
F
R
I
Q
T
K
G
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38859
116
13545
I72
H
P
L
K
Y
K
I
I
V
R
I
H
T
T
S
Baker's Yeast
Sacchar. cerevisiae
P28000
142
16132
S97
G
Y
S
I
P
H
P
S
E
N
L
L
N
I
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
N.A.
N.A.
90.2
N.A.
N.A.
63
65.4
64.6
56.3
N.A.
35.3
N.A.
29.1
42.1
Protein Similarity:
100
N.A.
100
N.A.
N.A.
94.7
N.A.
N.A.
71.8
73.6
74.4
67.6
N.A.
51.8
N.A.
52.7
60.9
P-Site Identity:
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
6.6
6.6
0
0
N.A.
6.6
N.A.
53.3
0
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
13.3
13.3
6.6
13.3
N.A.
26.6
N.A.
53.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
42.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
61.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
9
0
17
17
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
17
0
0
9
0
0
% D
% Glu:
9
9
0
0
0
0
0
0
42
0
0
0
9
0
17
% E
% Phe:
9
0
17
9
0
9
9
0
0
0
0
0
0
9
9
% F
% Gly:
42
0
0
0
0
0
9
9
9
9
9
0
9
0
0
% G
% His:
9
0
0
0
9
42
0
0
0
0
0
9
0
0
0
% H
% Ile:
17
9
9
9
25
9
9
17
9
0
17
34
0
9
0
% I
% Lys:
9
0
9
9
0
9
0
0
0
0
34
9
0
0
0
% K
% Leu:
0
0
9
9
0
0
0
9
9
0
17
9
9
25
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
17
25
0
0
9
0
0
9
9
0
0
34
0
0
% N
% Pro:
0
9
0
0
17
0
42
0
0
9
0
17
9
9
9
% P
% Gln:
0
9
0
9
0
17
9
0
9
9
0
0
0
0
0
% Q
% Arg:
0
9
0
25
9
9
9
25
9
9
9
9
0
9
42
% R
% Ser:
0
0
9
0
0
0
0
34
0
42
0
0
0
0
17
% S
% Thr:
9
0
25
25
34
0
17
9
0
0
9
0
9
9
0
% T
% Val:
0
0
0
9
0
0
0
0
9
0
0
17
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
0
9
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _