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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR1D
All Species:
14.24
Human Site:
Y121
Identified Species:
28.48
UniProt:
Q9Y2S0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2S0
NP_057056.1
133
15237
Y121
F
E
A
S
I
K
D
Y
K
D
Q
K
A
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110871
133
15192
Y121
F
E
A
S
I
K
D
Y
K
D
Q
K
A
S
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P97304
133
15054
Y121
F
E
A
S
I
K
D
Y
K
A
K
K
A
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514864
149
16940
Y105
F
E
A
S
V
K
E
Y
K
N
Q
M
E
A
Q
Chicken
Gallus gallus
XP_426271
114
12998
R103
D
T
F
E
K
S
M
R
K
Y
R
A
Q
R
E
Frog
Xenopus laevis
Q5XK67
114
13106
K103
N
T
F
E
T
S
I
K
E
Y
K
E
Q
K
E
Zebra Danio
Brachydanio rerio
Q6DRI4
112
12737
M101
L
Q
T
F
E
A
R
M
K
E
F
K
E
Q
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIZ0
105
11850
E94
T
I
V
T
F
E
K
E
M
A
E
F
N
A
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34476
144
16576
G133
Q
I
F
S
T
I
R
G
K
F
E
E
S
Y
E
Sea Urchin
Strong. purpuratus
XP_794921
117
13094
T106
I
Q
Q
T
F
K
D
T
I
Q
K
F
K
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38859
116
13545
Q104
E
L
D
Y
L
K
N
Q
F
E
A
E
V
A
K
Baker's Yeast
Sacchar. cerevisiae
P28000
142
16132
V130
D
L
M
D
L
C
D
V
V
E
S
K
F
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.2
N.A.
N.A.
90.2
N.A.
N.A.
63
65.4
64.6
56.3
N.A.
35.3
N.A.
29.1
42.1
Protein Similarity:
100
N.A.
100
N.A.
N.A.
94.7
N.A.
N.A.
71.8
73.6
74.4
67.6
N.A.
51.8
N.A.
52.7
60.9
P-Site Identity:
100
N.A.
100
N.A.
N.A.
80
N.A.
N.A.
53.3
6.6
0
13.3
N.A.
0
N.A.
13.3
13.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
93.3
N.A.
N.A.
86.6
13.3
20
26.6
N.A.
26.6
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
42.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.8
61.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
34
0
0
9
0
0
0
17
9
9
25
25
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
9
0
0
42
0
0
17
0
0
0
0
0
% D
% Glu:
9
34
0
17
9
9
9
9
9
25
17
25
17
9
42
% E
% Phe:
34
0
25
9
17
0
0
0
9
9
9
17
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
9
17
0
0
25
9
9
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
50
9
9
59
0
25
42
9
9
17
% K
% Leu:
9
17
0
0
17
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
9
9
9
0
0
9
0
0
9
% M
% Asn:
9
0
0
0
0
0
9
0
0
9
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
17
9
0
0
0
0
9
0
9
25
0
17
9
9
% Q
% Arg:
0
0
0
0
0
0
17
9
0
0
9
0
0
9
17
% R
% Ser:
0
0
0
42
0
17
0
0
0
0
9
0
9
25
0
% S
% Thr:
9
17
9
17
17
0
0
9
0
0
0
0
0
9
0
% T
% Val:
0
0
9
0
9
0
0
9
9
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
34
0
17
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _