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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CRYL1 All Species: 48.79
Human Site: S121 Identified Species: 89.44
UniProt: Q9Y2S2 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2S2 NP_057058.2 319 35419 S121 D D R V I L S S S T S C L M P
Chimpanzee Pan troglodytes XP_001147059 297 33340 S99 D D R V I L S S S T S C L M P
Rhesus Macaque Macaca mulatta XP_001086858 319 35329 S121 D D R V I L S S S T S C L M P
Dog Lupus familis XP_543175 319 35414 S121 D D K V V L S S S T S C L L P
Cat Felis silvestris
Mouse Mus musculus Q99KP3 319 35190 S121 D D R V I L S S S S S C L L P
Rat Rattus norvegicus Q811X6 319 35323 S121 D D Q V I L S S S S S C L L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518865 362 39761 S164 D D N I I I S S S S S C L L P
Chicken Gallus gallus NP_001026001 281 31242 S118 D D S V I L S S S T S C L L P
Frog Xenopus laevis NP_001091202 319 35836 S121 N D S T I I S S S T S C L S P
Zebra Danio Brachydanio rerio NP_001038806 315 35077 S121 S E S V I L S S S T S C L M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573114 315 34768 S120 G P N T I L S S S T S T F L P
Honey Bee Apis mellifera NP_001129207 317 35842 S120 D D K V I L S S S T S T F R P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794386 316 34985 S118 S D G A I L S S S S S C I M P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93 98.1 82.7 N.A. 84 84.6 N.A. 65.4 58.6 61.7 55.1 N.A. 51 51.4 N.A. 51.4
Protein Similarity: 100 93 99.6 91.8 N.A. 93.7 93 N.A. 79 73.9 81.5 75.8 N.A. 70.2 70.5 N.A. 72.4
P-Site Identity: 100 100 100 80 N.A. 86.6 80 N.A. 66.6 86.6 66.6 80 N.A. 53.3 73.3 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 93.3 80 86.6 N.A. 60 80 N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 85 0 0 0 % C
% Asp: 70 85 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 16 0 0 % F
% Gly: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 93 16 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 85 0 0 0 0 0 0 77 47 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 39 0 % M
% Asn: 8 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 100 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 31 0 0 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 16 0 24 0 0 0 100 100 100 31 100 0 0 8 0 % S
% Thr: 0 0 0 16 0 0 0 0 0 70 0 16 0 0 0 % T
% Val: 0 0 0 70 8 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _