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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CRYL1
All Species:
19.85
Human Site:
S3
Identified Species:
36.39
UniProt:
Q9Y2S2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2S2
NP_057058.2
319
35419
S3
_
_
_
_
_
M
A
S
S
A
A
G
C
V
V
Chimpanzee
Pan troglodytes
XP_001147059
297
33340
F3
_
_
_
_
_
M
L
F
A
S
G
G
F
Q
V
Rhesus Macaque
Macaca mulatta
XP_001086858
319
35329
S3
_
_
_
_
_
M
A
S
S
A
A
G
C
V
V
Dog
Lupus familis
XP_543175
319
35414
S3
_
_
_
_
_
M
A
S
S
E
P
G
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99KP3
319
35190
S3
_
_
_
_
_
M
A
S
P
A
A
G
G
V
V
Rat
Rattus norvegicus
Q811X6
319
35323
S3
_
_
_
_
_
M
A
S
P
A
A
G
G
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518865
362
39761
S46
A
A
A
E
K
M
T
S
T
E
D
D
S
V
V
Chicken
Gallus gallus
NP_001026001
281
31242
S11
T
H
V
A
I
I
G
S
G
L
I
G
C
S
W
Frog
Xenopus laevis
NP_001091202
319
35836
D3
_
_
_
_
_
M
N
D
L
Q
E
G
N
I
V
Zebra Danio
Brachydanio rerio
NP_001038806
315
35077
S3
_
_
_
_
_
M
S
S
L
K
E
K
I
I
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573114
315
34768
A3
_
_
_
_
_
M
S
A
K
N
E
K
V
G
I
Honey Bee
Apis mellifera
NP_001129207
317
35842
F3
_
_
_
_
_
M
S
F
K
N
E
K
I
G
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794386
316
34985
I8
M
E
S
Q
K
I
G
I
V
G
S
G
L
I
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
98.1
82.7
N.A.
84
84.6
N.A.
65.4
58.6
61.7
55.1
N.A.
51
51.4
N.A.
51.4
Protein Similarity:
100
93
99.6
91.8
N.A.
93.7
93
N.A.
79
73.9
81.5
75.8
N.A.
70.2
70.5
N.A.
72.4
P-Site Identity:
100
30
100
60
N.A.
80
80
N.A.
26.6
20
30
20
N.A.
10
10
N.A.
6.6
P-Site Similarity:
100
50
100
70
N.A.
80
80
N.A.
33.3
33.3
40
40
N.A.
40
30
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
39
8
8
31
31
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
24
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
8
8
0
0
% D
% Glu:
0
8
0
8
0
0
0
0
0
16
31
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
16
0
0
0
0
8
0
0
% F
% Gly:
0
0
0
0
0
0
16
0
8
8
8
70
16
16
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
16
0
8
0
0
8
0
16
24
16
% I
% Lys:
0
0
0
0
16
0
0
0
16
8
0
24
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
16
8
0
0
8
0
8
% L
% Met:
8
0
0
0
0
85
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
16
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
8
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
0
0
0
24
62
24
8
8
0
8
8
0
% S
% Thr:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
8
% T
% Val:
0
0
8
0
0
0
0
0
8
0
0
0
8
47
54
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
77
77
77
77
77
0
0
0
0
0
0
0
0
0
0
% _