Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AXIN2 All Species: 15.15
Human Site: S741 Identified Species: 30.3
UniProt: Q9Y2T1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T1 NP_004646.3 843 93558 S741 A T P F S N P S L A P E D H K
Chimpanzee Pan troglodytes XP_001162941 843 93520 S741 A T P F S N P S L A P E D H K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548025 843 93294 G741 A T P F S N P G L A S E D H K
Cat Felis silvestris
Mouse Mus musculus O88566 840 92916 S738 A S P F A N P S L A P E D H K
Rat Rattus norvegicus O70240 838 92929 S736 P T S F S N P S L A S E D H K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508740 844 93228 T741 G V L P F Y S T G L V P E D H
Chicken Gallus gallus O42400 841 94913 K742 R A G K L P L K Q R L K P Q K
Frog Xenopus laevis Q9YGY0 842 94441 Q742 K K A A K M P Q K Q R L K P Q
Zebra Danio Brachydanio rerio P57095 812 91479 S723 R K D P K K M S G C H S S L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V407 745 81700 P656 S I S L P H Q P P P L P A K P
Honey Bee Apis mellifera XP_001120373 693 78297 K604 Q S N Q S T L K K T K Q D I G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781992 855 95982 T749 T T G G K R P T S S S S S S K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 93 N.A. 89.9 90 N.A. 78.9 47.3 45 64.4 N.A. 21.9 24.9 N.A. 28.4
Protein Similarity: 100 99.5 N.A. 95.1 N.A. 93.5 93.4 N.A. 85.9 63.5 60.8 75.5 N.A. 37.8 42.4 N.A. 44.4
P-Site Identity: 100 100 N.A. 86.6 N.A. 86.6 80 N.A. 0 6.6 6.6 6.6 N.A. 0 13.3 N.A. 20
P-Site Similarity: 100 100 N.A. 86.6 N.A. 100 80 N.A. 13.3 13.3 13.3 6.6 N.A. 13.3 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 9 9 9 9 0 0 0 0 42 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 0 0 0 50 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 42 9 0 0 % E
% Phe: 0 0 0 42 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 17 9 0 0 0 9 17 0 0 0 0 0 17 % G
% His: 0 0 0 0 0 9 0 0 0 0 9 0 0 42 9 % H
% Ile: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % I
% Lys: 9 17 0 9 25 9 0 17 17 0 9 9 9 9 59 % K
% Leu: 0 0 9 9 9 0 17 0 42 9 17 9 0 9 0 % L
% Met: 0 0 0 0 0 9 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 0 42 0 0 0 0 0 0 0 0 0 % N
% Pro: 9 0 34 17 9 9 59 9 9 9 25 17 9 9 9 % P
% Gln: 9 0 0 9 0 0 9 9 9 9 0 9 0 9 9 % Q
% Arg: 17 0 0 0 0 9 0 0 0 9 9 0 0 0 0 % R
% Ser: 9 17 17 0 42 0 9 42 9 9 25 17 17 9 0 % S
% Thr: 9 42 0 0 0 9 0 17 0 9 0 0 0 0 0 % T
% Val: 0 9 0 0 0 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _