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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AXIN2 All Species: 16.06
Human Site: T419 Identified Species: 32.12
UniProt: Q9Y2T1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T1 NP_004646.3 843 93558 T419 N S R E G A P T Q H P L S L L
Chimpanzee Pan troglodytes XP_001162941 843 93520 T419 N S R E G A P T Q H P L S L L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_548025 843 93294 T419 S S R E G G P T P H P L S L L
Cat Felis silvestris
Mouse Mus musculus O88566 840 92916 A417 A L S S R D G A P V Q H P L A
Rat Rattus norvegicus O70240 838 92929 V419 S S R D G A P V Q H P L A L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508740 844 93228 S428 D L G A A S H S Q H P L S L L
Chicken Gallus gallus O42400 841 94913 S435 S S G P S V I S H K M P S A Q
Frog Xenopus laevis Q9YGY0 842 94441 S435 S S G P S V I S H K L P S G P
Zebra Danio Brachydanio rerio P57095 812 91479 A416 S E M S S S S A S H S L P L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V407 745 81700 S349 H G Y V Y N P S T T N T S Y V
Honey Bee Apis mellifera XP_001120373 693 78297 S297 A G L H A Q Y S S Y N P V S R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781992 855 95982 V431 P G T Q I F P V H D F V E D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 N.A. 93 N.A. 89.9 90 N.A. 78.9 47.3 45 64.4 N.A. 21.9 24.9 N.A. 28.4
Protein Similarity: 100 99.5 N.A. 95.1 N.A. 93.5 93.4 N.A. 85.9 63.5 60.8 75.5 N.A. 37.8 42.4 N.A. 44.4
P-Site Identity: 100 100 N.A. 80 N.A. 6.6 73.3 N.A. 46.6 13.3 13.3 26.6 N.A. 13.3 0 N.A. 6.6
P-Site Similarity: 100 100 N.A. 86.6 N.A. 6.6 93.3 N.A. 66.6 26.6 26.6 40 N.A. 33.3 13.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 9 17 25 0 17 0 0 0 0 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 9 0 9 0 0 0 9 0 0 0 9 9 % D
% Glu: 0 9 0 25 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % F
% Gly: 0 25 25 0 34 9 9 0 0 0 0 0 0 9 0 % G
% His: 9 0 0 9 0 0 9 0 25 50 0 9 0 0 0 % H
% Ile: 0 0 0 0 9 0 17 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % K
% Leu: 0 17 9 0 0 0 0 0 0 0 9 50 0 59 50 % L
% Met: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 17 0 0 0 0 9 0 0 0 0 17 0 0 0 0 % N
% Pro: 9 0 0 17 0 0 50 0 17 0 42 25 17 0 9 % P
% Gln: 0 0 0 9 0 9 0 0 34 0 9 0 0 0 9 % Q
% Arg: 0 0 34 0 9 0 0 0 0 0 0 0 0 0 9 % R
% Ser: 42 50 9 17 25 17 9 42 17 0 9 0 59 9 0 % S
% Thr: 0 0 9 0 0 0 0 25 9 9 0 9 0 0 0 % T
% Val: 0 0 0 9 0 17 0 17 0 9 0 9 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 9 0 9 0 0 9 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _