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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN2
All Species:
15.15
Human Site:
T437
Identified Species:
30.3
UniProt:
Q9Y2T1
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2T1
NP_004646.3
843
93558
T437
S
Y
E
E
D
P
Q
T
I
L
D
D
H
L
S
Chimpanzee
Pan troglodytes
XP_001162941
843
93520
T437
S
Y
E
E
D
P
Q
T
I
L
D
D
H
L
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548025
843
93294
T437
S
Y
E
E
D
P
Q
T
I
L
D
D
H
L
S
Cat
Felis silvestris
Mouse
Mus musculus
O88566
840
92916
P435
S
G
S
Y
E
E
D
P
Q
T
I
L
D
D
H
Rat
Rattus norvegicus
O70240
838
92929
T437
S
Y
E
E
D
P
Q
T
I
L
D
D
H
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
A446
R
Y
E
E
D
P
Q
A
I
L
D
D
H
L
S
Chicken
Gallus gallus
O42400
841
94913
E453
H
F
A
P
R
Y
S
E
M
G
C
A
G
M
Q
Frog
Xenopus laevis
Q9YGY0
842
94441
E453
H
F
N
S
R
Y
S
E
T
G
C
V
G
M
Q
Zebra Danio
Brachydanio rerio
P57095
812
91479
A434
T
C
E
E
D
P
Q
A
I
L
D
E
H
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
S367
R
V
D
S
E
R
A
S
V
S
S
G
G
R
T
Honey Bee
Apis mellifera
XP_001120373
693
78297
D315
E
L
Q
S
L
S
S
D
A
R
T
E
S
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
R449
I
L
E
D
H
M
S
R
V
F
K
D
S
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
93
N.A.
89.9
90
N.A.
78.9
47.3
45
64.4
N.A.
21.9
24.9
N.A.
28.4
Protein Similarity:
100
99.5
N.A.
95.1
N.A.
93.5
93.4
N.A.
85.9
63.5
60.8
75.5
N.A.
37.8
42.4
N.A.
44.4
P-Site Identity:
100
100
N.A.
100
N.A.
6.6
100
N.A.
86.6
0
0
73.3
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
100
N.A.
13.3
100
N.A.
86.6
20
13.3
86.6
N.A.
33.3
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
0
0
9
17
9
0
0
9
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
17
0
0
0
0
% C
% Asp:
0
0
9
9
50
0
9
9
0
0
50
50
9
17
0
% D
% Glu:
9
0
59
50
17
9
0
17
0
0
0
17
0
0
0
% E
% Phe:
0
17
0
0
0
0
0
0
0
9
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
17
0
9
25
0
0
% G
% His:
17
0
0
0
9
0
0
0
0
0
0
0
50
0
9
% H
% Ile:
9
0
0
0
0
0
0
0
50
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
17
0
0
9
0
0
0
0
50
0
9
0
50
0
% L
% Met:
0
0
0
0
0
9
0
0
9
0
0
0
0
17
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
9
% N
% Pro:
0
0
0
9
0
50
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
50
0
9
0
0
0
0
0
17
% Q
% Arg:
17
0
0
0
17
9
0
9
0
9
0
0
0
9
9
% R
% Ser:
42
0
9
25
0
9
34
9
0
9
9
0
17
0
50
% S
% Thr:
9
0
0
0
0
0
0
34
9
9
9
0
0
0
9
% T
% Val:
0
9
0
0
0
0
0
0
17
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
42
0
9
0
17
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _