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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AXIN2
All Species:
33.64
Human Site:
Y199
Identified Species:
67.27
UniProt:
Q9Y2T1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2T1
NP_004646.3
843
93558
Y199
T
S
D
I
Y
L
E
Y
V
R
S
G
G
E
N
Chimpanzee
Pan troglodytes
XP_001162941
843
93520
Y199
T
S
D
I
Y
L
E
Y
V
R
S
G
G
E
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548025
843
93294
Y199
T
S
D
I
Y
L
E
Y
V
R
S
G
G
E
N
Cat
Felis silvestris
Mouse
Mus musculus
O88566
840
92916
Y199
T
S
D
I
Y
L
E
Y
V
R
S
G
G
E
N
Rat
Rattus norvegicus
O70240
838
92929
Y199
T
S
D
I
Y
L
E
Y
V
R
S
G
G
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508740
844
93228
Y202
T
S
D
I
Y
L
E
Y
V
R
S
G
G
E
N
Chicken
Gallus gallus
O42400
841
94913
Y210
K
S
D
I
Y
L
E
Y
T
R
T
G
G
E
S
Frog
Xenopus laevis
Q9YGY0
842
94441
Y210
K
S
D
I
Y
L
E
Y
T
T
I
G
G
E
S
Zebra Danio
Brachydanio rerio
P57095
812
91479
D197
Y
Q
M
F
L
T
S
D
I
Y
L
E
Y
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V407
745
81700
K131
R
A
Q
I
K
A
I
K
T
N
P
E
I
P
L
Honey Bee
Apis mellifera
XP_001120373
693
78297
P79
T
T
M
E
S
D
S
P
P
A
C
L
R
W
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781992
855
95982
Y209
K
S
D
V
Y
V
Q
Y
V
N
N
G
G
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
N.A.
93
N.A.
89.9
90
N.A.
78.9
47.3
45
64.4
N.A.
21.9
24.9
N.A.
28.4
Protein Similarity:
100
99.5
N.A.
95.1
N.A.
93.5
93.4
N.A.
85.9
63.5
60.8
75.5
N.A.
37.8
42.4
N.A.
44.4
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
73.3
66.6
0
N.A.
6.6
6.6
N.A.
46.6
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
86.6
73.3
6.6
N.A.
13.3
13.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
75
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
67
0
0
0
0
17
0
67
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
75
75
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
75
0
0
9
0
9
0
9
0
9
0
0
% I
% Lys:
25
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
9
67
0
0
0
0
9
9
0
0
9
% L
% Met:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
17
9
0
0
0
50
% N
% Pro:
0
0
0
0
0
0
0
9
9
0
9
0
0
9
0
% P
% Gln:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
0
0
0
0
0
59
0
0
9
0
9
% R
% Ser:
0
75
0
0
9
0
17
0
0
0
50
0
0
0
25
% S
% Thr:
59
9
0
0
0
9
0
0
25
9
9
0
0
0
0
% T
% Val:
0
0
0
9
0
9
0
0
59
0
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
0
0
0
75
0
0
75
0
9
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _