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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3M1 All Species: 32.12
Human Site: S219 Identified Species: 50.48
UniProt: Q9Y2T2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T2 NP_036227.1 418 46939 S219 L S G M P D L S L S F M N P R
Chimpanzee Pan troglodytes XP_001141331 436 49226 T219 L T G M P D L T L S F M N P R
Rhesus Macaque Macaca mulatta XP_001098843 418 46925 S219 L S G M P D L S L S F M N P R
Dog Lupus familis XP_546170 477 52895 S278 L S G M P D L S L S F M N P R
Cat Felis silvestris
Mouse Mus musculus Q9JKC8 418 46918 S219 L S G M P D L S L S F M N P R
Rat Rattus norvegicus P53676 418 46963 S219 L S G M P D L S L S F M N P R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506462 418 46967 S219 L S G M P D L S L S F M N P R
Chicken Gallus gallus Q5ZMP7 418 46954 S219 L S G M P D L S L S F M N P R
Frog Xenopus laevis Q801Q8 435 49666 G234 K G T A D E T G K T G K Q S I
Zebra Danio Brachydanio rerio Q6NWK2 436 49641 G235 G G T T D D A G K S G K Q S I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788873 415 46777 L216 K L S G M P D L T L S F M N P
Honey Bee Apis mellifera XP_624899 417 47249 L218 K L S G M P D L T L S F M N P
Nematode Worm Caenorhab. elegans P35602 422 48210 G223 K V L F E G S G R G K S K S V
Sea Urchin Strong. purpuratus XP_788000 416 46931 D217 V K L T G M P D L T M S F V N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00776 475 53855 T263 S I T S S S A T N K K K V N I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 99.7 87.6 N.A. 99.5 98.8 N.A. 97.3 95.4 25.7 25.4 N.A. 69.1 71.5 26 74.8
Protein Similarity: 100 90.8 99.7 87.6 N.A. 99.7 99.5 N.A. 99.5 97.8 49.4 49 N.A. 85.1 86.1 51.9 89.7
P-Site Identity: 100 86.6 100 100 N.A. 100 100 N.A. 100 100 0 13.3 N.A. 0 0 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 100 13.3 13.3 N.A. 0 0 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 7 0 0 14 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 14 60 14 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 0 0 54 14 7 0 0 % F
% Gly: 7 14 54 14 7 7 0 20 0 7 14 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 20 % I
% Lys: 27 7 0 0 0 0 0 0 14 7 14 20 7 0 0 % K
% Leu: 54 14 14 0 0 0 54 14 60 14 0 0 0 0 0 % L
% Met: 0 0 0 54 14 7 0 0 0 0 7 54 14 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 7 0 0 0 54 20 7 % N
% Pro: 0 0 0 0 54 14 7 0 0 0 0 0 0 54 14 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 14 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 54 % R
% Ser: 7 47 14 7 7 7 7 47 0 60 14 14 0 20 0 % S
% Thr: 0 7 20 14 0 0 7 14 14 14 0 0 0 0 0 % T
% Val: 7 7 0 0 0 0 0 0 0 0 0 0 7 7 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _