Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3M1 All Species: 30.91
Human Site: S286 Identified Species: 48.57
UniProt: Q9Y2T2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T2 NP_036227.1 418 46939 S286 S I S F K E N S S C G R F D I
Chimpanzee Pan troglodytes XP_001141331 436 49226 S286 N I S F R D S S S L G R F E I
Rhesus Macaque Macaca mulatta XP_001098843 418 46925 S286 S I S F K E N S S C G R F D I
Dog Lupus familis XP_546170 477 52895 S345 S I S F K E N S S C G R F D I
Cat Felis silvestris
Mouse Mus musculus Q9JKC8 418 46918 S286 S I S F K E N S S C G R F D I
Rat Rattus norvegicus P53676 418 46963 S286 N I S F K E N S S C G R F D I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506462 418 46967 S286 N I S F K E N S S C G R F D V
Chicken Gallus gallus Q5ZMP7 418 46954 S286 L I S F K E N S S S G R F D V
Frog Xenopus laevis Q801Q8 435 49666 L301 R E V G R T K L E V K V V I K
Zebra Danio Brachydanio rerio Q6NWK2 436 49641 L302 R E V G R T K L E V K V V I K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788873 415 46777 G283 H N F S I K T G E Q G R L D L
Honey Bee Apis mellifera XP_624899 417 47249 L285 H N I S L K E L G G G R L D I
Nematode Worm Caenorhab. elegans P35602 422 48210 V290 E R H S H S R V S F I I K A K
Sea Urchin Strong. purpuratus XP_788000 416 46931 E284 K P N I M M R E T S G R F E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00776 475 53855 I330 Q V H S N S R I E I H C K A K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 99.7 87.6 N.A. 99.5 98.8 N.A. 97.3 95.4 25.7 25.4 N.A. 69.1 71.5 26 74.8
Protein Similarity: 100 90.8 99.7 87.6 N.A. 99.7 99.5 N.A. 99.5 97.8 49.4 49 N.A. 85.1 86.1 51.9 89.7
P-Site Identity: 100 60 100 100 N.A. 100 93.3 N.A. 86.6 80 0 0 N.A. 20 26.6 6.6 20
P-Site Similarity: 100 93.3 100 100 N.A. 100 100 N.A. 100 86.6 6.6 6.6 N.A. 33.3 33.3 6.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 40 0 7 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 0 0 0 0 0 60 0 % D
% Glu: 7 14 0 0 0 47 7 7 27 0 0 0 0 14 0 % E
% Phe: 0 0 7 54 0 0 0 0 0 7 0 0 60 0 0 % F
% Gly: 0 0 0 14 0 0 0 7 7 7 74 0 0 0 0 % G
% His: 14 0 14 0 7 0 0 0 0 0 7 0 0 0 0 % H
% Ile: 0 54 7 7 7 0 0 7 0 7 7 7 0 14 47 % I
% Lys: 7 0 0 0 47 14 14 0 0 0 14 0 14 0 27 % K
% Leu: 7 0 0 0 7 0 0 20 0 7 0 0 14 0 7 % L
% Met: 0 0 0 0 7 7 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 14 7 0 7 0 47 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 14 7 0 0 20 0 20 0 0 0 0 74 0 0 0 % R
% Ser: 27 0 54 27 0 14 7 54 60 14 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 14 7 0 7 0 0 0 0 0 0 % T
% Val: 0 7 14 0 0 0 0 7 0 14 0 14 14 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _