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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP3M1 All Species: 28.48
Human Site: S50 Identified Species: 44.76
UniProt: Q9Y2T2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2T2 NP_036227.1 418 46939 S50 E N V P P V I S T P H H Y L I
Chimpanzee Pan troglodytes XP_001141331 436 49226 P50 E N V P P V I P T P H H Y L L
Rhesus Macaque Macaca mulatta XP_001098843 418 46925 S50 E N V P P V I S T P H H Y L I
Dog Lupus familis XP_546170 477 52895 S109 E N V P P V I S T P H H Y L I
Cat Felis silvestris
Mouse Mus musculus Q9JKC8 418 46918 S50 E N V P P V I S T P H H Y L I
Rat Rattus norvegicus P53676 418 46963 S50 E N V P T V I S T P H H Y L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506462 418 46967 S50 E N V P P V I S T P H H Y L I
Chicken Gallus gallus Q5ZMP7 418 46954 S50 E N V P P V I S T P L H Y L I
Frog Xenopus laevis Q801Q8 435 49666 N49 Q V R S P V T N I A R T S F F
Zebra Danio Brachydanio rerio Q6NWK2 436 49641 N49 Q V R S P V T N I A R T S F F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788873 415 46777 A48 Y D V P P V I A T P H Y Y L I
Honey Bee Apis mellifera XP_624899 417 47249 A50 E D T P P V I A T P H H Y L I
Nematode Worm Caenorhab. elegans P35602 422 48210 T51 G S A A P V L T Y Q D T N F V
Sea Urchin Strong. purpuratus XP_788000 416 46931 A50 L D V P P I I A T P H H Y L I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q00776 475 53855 N51 N L I P P C L N H N G L E Y L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.7 99.7 87.6 N.A. 99.5 98.8 N.A. 97.3 95.4 25.7 25.4 N.A. 69.1 71.5 26 74.8
Protein Similarity: 100 90.8 99.7 87.6 N.A. 99.7 99.5 N.A. 99.5 97.8 49.4 49 N.A. 85.1 86.1 51.9 89.7
P-Site Identity: 100 86.6 100 100 N.A. 100 93.3 N.A. 100 93.3 13.3 13.3 N.A. 73.3 80 13.3 73.3
P-Site Similarity: 100 93.3 100 100 N.A. 100 93.3 N.A. 100 93.3 26.6 26.6 N.A. 93.3 93.3 40 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 47.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 0 20 0 14 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 20 0 0 0 0 0 0 0 0 7 0 0 0 0 % D
% Glu: 60 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 14 % F
% Gly: 7 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 7 0 67 67 0 0 0 % H
% Ile: 0 0 7 0 0 7 74 0 14 0 0 0 0 0 67 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 7 7 0 0 0 0 14 0 0 0 7 7 0 74 14 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 54 0 0 0 0 0 20 0 7 0 0 7 0 0 % N
% Pro: 0 0 0 80 94 0 0 7 0 74 0 0 0 0 0 % P
% Gln: 14 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 14 0 0 0 0 0 0 0 14 0 0 0 0 % R
% Ser: 0 7 0 14 0 0 0 47 0 0 0 0 14 0 0 % S
% Thr: 0 0 7 0 7 0 14 7 74 0 0 20 0 0 0 % T
% Val: 0 14 67 0 0 87 0 0 0 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 7 0 0 7 74 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _